TY  - JOUR
AU  - Finimundy, Tiane C.
AU  - Karkanis, Anestis
AU  - Fernandes, Ângela
AU  - Petropoulos, Spyridon A.
AU  - Calhelha, Ricardo
AU  - Petrović, Jovana
AU  - Soković, Marina
AU  - Rosa, Eduardo
AU  - Barros, Lillian
AU  - Ferreira, Isabel C F R
PY  - 2020
UR  - http://www.ncbi.nlm.nih.gov/pubmed/32470801
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/3694
AB  - In this study, the chemical characterization and bioactive properties of S. minor cultivated under different fertilization rates (control, half rate and full rate) were evaluated. Twenty-two phenolic compounds were identified, including five phenolic acids, seven flavonoids and ten tannins. Hydrolysable tannins were prevalent, namely Sanguiin H-10, especially in leaves without fertilization (control). Roots of full-rate fertilizer (660 Kg/ha) presented the highest flavonoid content, mainly catechin and its isomers, whereas half-rate fertilizer (330 Kg/ha), presented the highest content of total phenolic compounds, due to the higher amount of ellagitannins (lambertianin C: 84 ± 1 mg/g of dry extract). Antimicrobial activities were also promising, especially against Salmonella typhimurium (MBC = 0.44 mg/mL). Moreover, root samples revealed activity against all tested cell lines regardless of fertilization rate, whereas leaves were effective only against HeLa cell line. In conclusion, S. minor could be a source of natural bioactive compounds, while fertilization could increase phenolic compounds content.
PB  - Elsevier Ltd
T2  - Food Chemistry
T1  - Bioactive properties of Sanguisorba minor L. cultivated in central Greece under different fertilization regimes.
VL  - 327
DO  - 10.1016/j.foodchem.2020.127043
SP  - 127043
ER  - 

@article{
author = "Finimundy, Tiane C. and Karkanis, Anestis and Fernandes, Ângela and Petropoulos, Spyridon A. and Calhelha, Ricardo and Petrović, Jovana and Soković, Marina and Rosa, Eduardo and Barros, Lillian and Ferreira, Isabel C F R",
year = "2020",
abstract = "In this study, the chemical characterization and bioactive properties of S. minor cultivated under different fertilization rates (control, half rate and full rate) were evaluated. Twenty-two phenolic compounds were identified, including five phenolic acids, seven flavonoids and ten tannins. Hydrolysable tannins were prevalent, namely Sanguiin H-10, especially in leaves without fertilization (control). Roots of full-rate fertilizer (660 Kg/ha) presented the highest flavonoid content, mainly catechin and its isomers, whereas half-rate fertilizer (330 Kg/ha), presented the highest content of total phenolic compounds, due to the higher amount of ellagitannins (lambertianin C: 84 ± 1 mg/g of dry extract). Antimicrobial activities were also promising, especially against Salmonella typhimurium (MBC = 0.44 mg/mL). Moreover, root samples revealed activity against all tested cell lines regardless of fertilization rate, whereas leaves were effective only against HeLa cell line. In conclusion, S. minor could be a source of natural bioactive compounds, while fertilization could increase phenolic compounds content.",
publisher = "Elsevier Ltd",
journal = "Food Chemistry",
title = "Bioactive properties of Sanguisorba minor L. cultivated in central Greece under different fertilization regimes.",
volume = "327",
doi = "10.1016/j.foodchem.2020.127043",
pages = "127043"
}

Finimundy, T. C., Karkanis, A., Fernandes, Â., Petropoulos, S. A., Calhelha, R., Petrović, J., Soković, M., Rosa, E., Barros, L.,& Ferreira, I. C. F. R.. (2020). Bioactive properties of Sanguisorba minor L. cultivated in central Greece under different fertilization regimes.. in Food Chemistry
Elsevier Ltd., 327, 127043.
https://doi.org/10.1016/j.foodchem.2020.127043

Finimundy TC, Karkanis A, Fernandes Â, Petropoulos SA, Calhelha R, Petrović J, Soković M, Rosa E, Barros L, Ferreira ICFR. Bioactive properties of Sanguisorba minor L. cultivated in central Greece under different fertilization regimes.. in Food Chemistry. 2020;327:127043.
doi:10.1016/j.foodchem.2020.127043 .

Finimundy, Tiane C., Karkanis, Anestis, Fernandes, Ângela, Petropoulos, Spyridon A., Calhelha, Ricardo, Petrović, Jovana, Soković, Marina, Rosa, Eduardo, Barros, Lillian, Ferreira, Isabel C F R, "Bioactive properties of Sanguisorba minor L. cultivated in central Greece under different fertilization regimes." in Food Chemistry, 327 (2020):127043,
https://doi.org/10.1016/j.foodchem.2020.127043 . .

TY  - JOUR
AU  - Finimundy, Tiane C.
AU  - Pereira, Carla
AU  - Dias, Maria Inês
AU  - Caleja, Cristina
AU  - Calhelha, Ricardo C.
AU  - Soković, Marina
AU  - Stojković, Dejan
AU  - Carvalho, Ana Maria
AU  - Rosa, Eduardo
AU  - Barros, Lillian
AU  - Ferreira, Isabel C. F. R.
PY  - 2020
UR  - https://www.mdpi.com/1420-3049/25/9/2151
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/3677
AB  - Several plants have been used for medicinal applications and have been traditionally consumed as decoctions and infusions. Although some herbs are used alone as a beverage, they are often blended in mixtures to maximize their effects. Herein, the nutritional characterization of six infusions from herbal blends was evaluated using the official methods of analysis (AOAC international). A further characterization of the individual phenolic profile was also performed by HPLC-DAD/ESI-MSn, and finally bioactive potential was determined by evaluating the antioxidant, cytotoxic, anti-inflammatory, and antimicrobial activities of each blend. The wide variety of plants in each sample led to variability in the results for all analyzed parameters. However, blends containing 15% Laurus nobilis L. and 15% Juglan regia L. in their composition showed higher sugar content and energy contribution; higher concentration of phenolic compounds (phenolic acids and flavonoids); greater antioxidant, cytotoxic, and anti-inflammatory capacity; and also better antimicrobial effects against all the tested bacterial and fungal strains. Further studies will be necessary to evaluate the real synergistic effects that these two species show in the presence of other plants, and to evaluate their potential for application in various food, pharmaceutical, and nutraceutical products as infusion preparations.
PB  - NLM (Medline)
T2  - Molecules
T1  - Infusions of Herbal Blends as Promising Sources of Phenolic Compounds and Bioactive Properties
IS  - 9
VL  - 25
DO  - 10.3390/molecules25092151
SP  - 2151
ER  - 

@article{
author = "Finimundy, Tiane C. and Pereira, Carla and Dias, Maria Inês and Caleja, Cristina and Calhelha, Ricardo C. and Soković, Marina and Stojković, Dejan and Carvalho, Ana Maria and Rosa, Eduardo and Barros, Lillian and Ferreira, Isabel C. F. R.",
year = "2020",
abstract = "Several plants have been used for medicinal applications and have been traditionally consumed as decoctions and infusions. Although some herbs are used alone as a beverage, they are often blended in mixtures to maximize their effects. Herein, the nutritional characterization of six infusions from herbal blends was evaluated using the official methods of analysis (AOAC international). A further characterization of the individual phenolic profile was also performed by HPLC-DAD/ESI-MSn, and finally bioactive potential was determined by evaluating the antioxidant, cytotoxic, anti-inflammatory, and antimicrobial activities of each blend. The wide variety of plants in each sample led to variability in the results for all analyzed parameters. However, blends containing 15% Laurus nobilis L. and 15% Juglan regia L. in their composition showed higher sugar content and energy contribution; higher concentration of phenolic compounds (phenolic acids and flavonoids); greater antioxidant, cytotoxic, and anti-inflammatory capacity; and also better antimicrobial effects against all the tested bacterial and fungal strains. Further studies will be necessary to evaluate the real synergistic effects that these two species show in the presence of other plants, and to evaluate their potential for application in various food, pharmaceutical, and nutraceutical products as infusion preparations.",
publisher = "NLM (Medline)",
journal = "Molecules",
title = "Infusions of Herbal Blends as Promising Sources of Phenolic Compounds and Bioactive Properties",
number = "9",
volume = "25",
doi = "10.3390/molecules25092151",
pages = "2151"
}

Finimundy, T. C., Pereira, C., Dias, M. I., Caleja, C., Calhelha, R. C., Soković, M., Stojković, D., Carvalho, A. M., Rosa, E., Barros, L.,& Ferreira, I. C. F. R.. (2020). Infusions of Herbal Blends as Promising Sources of Phenolic Compounds and Bioactive Properties. in Molecules
NLM (Medline)., 25(9), 2151.
https://doi.org/10.3390/molecules25092151

Finimundy TC, Pereira C, Dias MI, Caleja C, Calhelha RC, Soković M, Stojković D, Carvalho AM, Rosa E, Barros L, Ferreira ICFR. Infusions of Herbal Blends as Promising Sources of Phenolic Compounds and Bioactive Properties. in Molecules. 2020;25(9):2151.
doi:10.3390/molecules25092151 .

Finimundy, Tiane C., Pereira, Carla, Dias, Maria Inês, Caleja, Cristina, Calhelha, Ricardo C., Soković, Marina, Stojković, Dejan, Carvalho, Ana Maria, Rosa, Eduardo, Barros, Lillian, Ferreira, Isabel C. F. R., "Infusions of Herbal Blends as Promising Sources of Phenolic Compounds and Bioactive Properties" in Molecules, 25, no. 9 (2020):2151,
https://doi.org/10.3390/molecules25092151 . .

TY  - JOUR
AU  - Caleja, Cristina
AU  - Finimundy, Tiane C.
AU  - Pereira, Carla
AU  - Barros, Lillian
AU  - Calhelha, Ricardo C.
AU  - Soković, Marina
AU  - Ivanov, Marija
AU  - Carvalho, Ana Maria
AU  - Rosa, Eduardo
AU  - Ferreira, Isabel C. F. R.
PY  - 2019
UR  - http://xlink.rsc.org/?DOI=C9FO01473J
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/3481
AB  - In order to characterize and study the bioactivities of individual plant species and to determine how these characteristics are modified when preparing blends, five different plant species were selected: Erica australis L., Genista tridentata L., Melissa officinalis L., Mentha spicata L., and Prunella vulgaris L. Infusions prepared from each plant species and from three selected mixtures were analyzed in terms of nutritional values, phenolic compositions, and bioactive properties (antioxidant, antimicrobial, cytotoxic, and anti-inflammatory activities). The major compound detected in M. officinalis, M. spicata, and P. vulgaris infusions was rosmarinic acid, whilst in E. australis and G. tridentata flavonoid derivatives such as quercetin and genistein were identified. P. vulgaris and M. officinalis presented the best results in TBARS and OxHLIA assays, respectively. M. spicata and all mixtures presented anti-inflammatory activity. M. spicata showed the best cytotoxic properties and antimicrobial activity, and none of the infusions showed hepatotoxicity for non-tumour cells.
T2  - Food & Function
T1  - Challenges of traditional herbal teas: plant infusions and their mixtures with bioactive properties.
IS  - 9
VL  - 10
DO  - 10.1039/c9fo01473j
SP  - 5939
EP  - 5951
ER  - 

@article{
author = "Caleja, Cristina and Finimundy, Tiane C. and Pereira, Carla and Barros, Lillian and Calhelha, Ricardo C. and Soković, Marina and Ivanov, Marija and Carvalho, Ana Maria and Rosa, Eduardo and Ferreira, Isabel C. F. R.",
year = "2019",
abstract = "In order to characterize and study the bioactivities of individual plant species and to determine how these characteristics are modified when preparing blends, five different plant species were selected: Erica australis L., Genista tridentata L., Melissa officinalis L., Mentha spicata L., and Prunella vulgaris L. Infusions prepared from each plant species and from three selected mixtures were analyzed in terms of nutritional values, phenolic compositions, and bioactive properties (antioxidant, antimicrobial, cytotoxic, and anti-inflammatory activities). The major compound detected in M. officinalis, M. spicata, and P. vulgaris infusions was rosmarinic acid, whilst in E. australis and G. tridentata flavonoid derivatives such as quercetin and genistein were identified. P. vulgaris and M. officinalis presented the best results in TBARS and OxHLIA assays, respectively. M. spicata and all mixtures presented anti-inflammatory activity. M. spicata showed the best cytotoxic properties and antimicrobial activity, and none of the infusions showed hepatotoxicity for non-tumour cells.",
journal = "Food & Function",
title = "Challenges of traditional herbal teas: plant infusions and their mixtures with bioactive properties.",
number = "9",
volume = "10",
doi = "10.1039/c9fo01473j",
pages = "5939-5951"
}

Caleja, C., Finimundy, T. C., Pereira, C., Barros, L., Calhelha, R. C., Soković, M., Ivanov, M., Carvalho, A. M., Rosa, E.,& Ferreira, I. C. F. R.. (2019). Challenges of traditional herbal teas: plant infusions and their mixtures with bioactive properties.. in Food & Function, 10(9), 5939-5951.
https://doi.org/10.1039/c9fo01473j

Caleja C, Finimundy TC, Pereira C, Barros L, Calhelha RC, Soković M, Ivanov M, Carvalho AM, Rosa E, Ferreira ICFR. Challenges of traditional herbal teas: plant infusions and their mixtures with bioactive properties.. in Food & Function. 2019;10(9):5939-5951.
doi:10.1039/c9fo01473j .

Caleja, Cristina, Finimundy, Tiane C., Pereira, Carla, Barros, Lillian, Calhelha, Ricardo C., Soković, Marina, Ivanov, Marija, Carvalho, Ana Maria, Rosa, Eduardo, Ferreira, Isabel C. F. R., "Challenges of traditional herbal teas: plant infusions and their mixtures with bioactive properties." in Food & Function, 10, no. 9 (2019):5939-5951,
https://doi.org/10.1039/c9fo01473j . .