TY  - JOUR
AU  - Petrović, Nada V.
AU  - Petrović, Slobodan S.
AU  - Džamić, Ana M.
AU  - Ćirić, Ana
AU  - Ristić, Mihailo S.
AU  - Milovanović, Stoja L.
AU  - Petrović, Slobodan D.
PY  - 2016
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/6743
AB  - The chemical composition, antimicrobial and antioxidant activity of Thymus praecox extracts obtained by
fractional supercritical fluid extraction (SFE) with carbon dioxide were investigated. Properties of super critical extracts and extracts obtained by Soxhlet extraction were compared. The chemical composition
of extracts was determined using GC–FID and GC–MS analytical methods. The antimicrobial activity of
extracts was evaluated against 16 pathogenic microorganisms using microdilution method. Antioxidant
potential of extracts to neutralize DPPH radicals was also investigated. Investigated supercritical extracts
showed better antimicrobial activity than commercial antibiotics (streptomycin and ampicillin) and com mercial fungicides (bifonazol and ketoconazole) against all tested strains. For bacteria MIC and MBC were
38–200  g/ml and 75–300  g/ml, respectively, while for fungi MIC and MFC were 17–150  g/ml and
35–300  g/ml, respectively.
PB  - Elsevier B.V
T2  - The Journal of Supercritical Fluids
T1  - Chemical composition, antioxidant and antimicrobial activity of Thymus praecox supercritical extracts
VL  - 110
DO  - 10.1016/j.supflu.2016.01.001
SP  - 117
EP  - 125
ER  - 

@article{
author = "Petrović, Nada V. and Petrović, Slobodan S. and Džamić, Ana M. and Ćirić, Ana and Ristić, Mihailo S. and Milovanović, Stoja L. and Petrović, Slobodan D.",
year = "2016",
abstract = "The chemical composition, antimicrobial and antioxidant activity of Thymus praecox extracts obtained by
fractional supercritical fluid extraction (SFE) with carbon dioxide were investigated. Properties of super critical extracts and extracts obtained by Soxhlet extraction were compared. The chemical composition
of extracts was determined using GC–FID and GC–MS analytical methods. The antimicrobial activity of
extracts was evaluated against 16 pathogenic microorganisms using microdilution method. Antioxidant
potential of extracts to neutralize DPPH radicals was also investigated. Investigated supercritical extracts
showed better antimicrobial activity than commercial antibiotics (streptomycin and ampicillin) and com mercial fungicides (bifonazol and ketoconazole) against all tested strains. For bacteria MIC and MBC were
38–200  g/ml and 75–300  g/ml, respectively, while for fungi MIC and MFC were 17–150  g/ml and
35–300  g/ml, respectively.",
publisher = "Elsevier B.V",
journal = "The Journal of Supercritical Fluids",
title = "Chemical composition, antioxidant and antimicrobial activity of Thymus praecox supercritical extracts",
volume = "110",
doi = "10.1016/j.supflu.2016.01.001",
pages = "117-125"
}

Petrović, N. V., Petrović, S. S., Džamić, A. M., Ćirić, A., Ristić, M. S., Milovanović, S. L.,& Petrović, S. D.. (2016). Chemical composition, antioxidant and antimicrobial activity of Thymus praecox supercritical extracts. in The Journal of Supercritical Fluids
Elsevier B.V., 110, 117-125.
https://doi.org/10.1016/j.supflu.2016.01.001

Petrović NV, Petrović SS, Džamić AM, Ćirić A, Ristić MS, Milovanović SL, Petrović SD. Chemical composition, antioxidant and antimicrobial activity of Thymus praecox supercritical extracts. in The Journal of Supercritical Fluids. 2016;110:117-125.
doi:10.1016/j.supflu.2016.01.001 .

Petrović, Nada V., Petrović, Slobodan S., Džamić, Ana M., Ćirić, Ana, Ristić, Mihailo S., Milovanović, Stoja L., Petrović, Slobodan D., "Chemical composition, antioxidant and antimicrobial activity of Thymus praecox supercritical extracts" in The Journal of Supercritical Fluids, 110 (2016):117-125,
https://doi.org/10.1016/j.supflu.2016.01.001 . .

TY  - JOUR
AU  - Soković, Marina
AU  - Marin, Petar D
AU  - Simić, Draga M
AU  - Knežević-Vukčević, Jelena
AU  - Vajs, Vlatka E
AU  - Petrović, Slobodan D
PY  - 2002
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/1808
AB  - The present study was carried out to investigate the antimutagenic activity of essential oil and crude extract of Phlomis fruticosa. This species belongs to the family Lamiaceae which includes a number of species with medical and pharmaceutical properties. The Escherichia coli K12 reversion assay for identifying antimutagens was used. The number of spontaneous and UV-induced Arg(+) revertants, as well as cell survival was monitored in the presence of non-toxic concentrations of the essential oil. The number of UV-induced revertants was slightly increased in the presence of essential oil. The ethanol extract demonstrated a significant effect on viable cells. Study on pharmacological and phytochemical activities as well as antimutagenetic potential against some chemical mutagens of the essential oils, total extract and their different fractions and constituents of Ph. fruticosa is in progress.
T2  - Pharmaceutical Biology
T1  - Antimutagenic activity of essential oil and crude extract of Phlomis fruticosa
IS  - 4
VL  - 40
EP  - 314
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_1808
ER  - 

@article{
author = "Soković, Marina and Marin, Petar D and Simić, Draga M and Knežević-Vukčević, Jelena and Vajs, Vlatka E and Petrović, Slobodan D",
year = "2002",
abstract = "The present study was carried out to investigate the antimutagenic activity of essential oil and crude extract of Phlomis fruticosa. This species belongs to the family Lamiaceae which includes a number of species with medical and pharmaceutical properties. The Escherichia coli K12 reversion assay for identifying antimutagens was used. The number of spontaneous and UV-induced Arg(+) revertants, as well as cell survival was monitored in the presence of non-toxic concentrations of the essential oil. The number of UV-induced revertants was slightly increased in the presence of essential oil. The ethanol extract demonstrated a significant effect on viable cells. Study on pharmacological and phytochemical activities as well as antimutagenetic potential against some chemical mutagens of the essential oils, total extract and their different fractions and constituents of Ph. fruticosa is in progress.",
journal = "Pharmaceutical Biology",
title = "Antimutagenic activity of essential oil and crude extract of Phlomis fruticosa",
number = "4",
volume = "40",
pages = "314",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_1808"
}

Soković, M., Marin, P. D., Simić, D. M., Knežević-Vukčević, J., Vajs, V. E.,& Petrović, S. D.. (2002). Antimutagenic activity of essential oil and crude extract of Phlomis fruticosa. in Pharmaceutical Biology, 40(4).
https://hdl.handle.net/21.15107/rcub_ibiss_1808

Soković M, Marin PD, Simić DM, Knežević-Vukčević J, Vajs VE, Petrović SD. Antimutagenic activity of essential oil and crude extract of Phlomis fruticosa. in Pharmaceutical Biology. 2002;40(4):null-314.
https://hdl.handle.net/21.15107/rcub_ibiss_1808 .

Soković, Marina, Marin, Petar D, Simić, Draga M, Knežević-Vukčević, Jelena, Vajs, Vlatka E, Petrović, Slobodan D, "Antimutagenic activity of essential oil and crude extract of Phlomis fruticosa" in Pharmaceutical Biology, 40, no. 4 (2002),
https://hdl.handle.net/21.15107/rcub_ibiss_1808 .