TY  - JOUR
AU  - Poznanović, Goran
AU  - Martinović, Vesna
AU  - Ivanović-Matić, Svetlana
AU  - Ševaljević, Ljiljana
PY  - 1994
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/5643
AB  - The effect of the acute phase response on the affinity of binding between nuclear matrix proteins and the rat haptoglobin (Hp) gene region was examined. Nuclear matrices isolated from acute phase livers were enriched with the 5' Hp gene flanking region (-705/+159), but not with the spliced, protein-coding sequence. Reassociation experiments with isolated nuclear protein matrix spheres and end-labeled fragments I (-146/+156), II (-146/-541), and III (-541/-705) revealed that the matrix proteins displayed an increased binding potential during the acute phase response for all of the examined regions, this being most pronounced for fragment II. BAL 31 digestion of fragment II showed that the sequence element that was responsible for the increased association with nuclear matrix proteins during the acute phase response was a tract of 38 adenine bases. The DNA region established stable associations with nuclear lamin B (67 kDa, pI 5.7) in the controls, and with lamins A (69 kDa, pI 7.0), B, isoforms of lamin C (62 kDa, pI 6.55-6.95), and a 55-kDa (pI 5.9) polypeptide during the acute phase response. Sequence ABC (-165/-56), which overlaps fragments I and II and represents the Hp cis-acting element, did not bind to the non-histone nuclear matrix proteins.
PB  - Oxford, UK: Oxford University Press
T2  - Journal of Biochemistry
T1  - Regions of the haptoglobin 5' flanking gene sequence show different binding affinities to nuclear matrix proteins during the acute phase response
IS  - 3
VL  - 115
DO  - 10.1093/oxfordjournals.jbchem.a124354
SP  - 422
EP  - 428
ER  - 

@article{
author = "Poznanović, Goran and Martinović, Vesna and Ivanović-Matić, Svetlana and Ševaljević, Ljiljana",
year = "1994",
abstract = "The effect of the acute phase response on the affinity of binding between nuclear matrix proteins and the rat haptoglobin (Hp) gene region was examined. Nuclear matrices isolated from acute phase livers were enriched with the 5' Hp gene flanking region (-705/+159), but not with the spliced, protein-coding sequence. Reassociation experiments with isolated nuclear protein matrix spheres and end-labeled fragments I (-146/+156), II (-146/-541), and III (-541/-705) revealed that the matrix proteins displayed an increased binding potential during the acute phase response for all of the examined regions, this being most pronounced for fragment II. BAL 31 digestion of fragment II showed that the sequence element that was responsible for the increased association with nuclear matrix proteins during the acute phase response was a tract of 38 adenine bases. The DNA region established stable associations with nuclear lamin B (67 kDa, pI 5.7) in the controls, and with lamins A (69 kDa, pI 7.0), B, isoforms of lamin C (62 kDa, pI 6.55-6.95), and a 55-kDa (pI 5.9) polypeptide during the acute phase response. Sequence ABC (-165/-56), which overlaps fragments I and II and represents the Hp cis-acting element, did not bind to the non-histone nuclear matrix proteins.",
publisher = "Oxford, UK: Oxford University Press",
journal = "Journal of Biochemistry",
title = "Regions of the haptoglobin 5' flanking gene sequence show different binding affinities to nuclear matrix proteins during the acute phase response",
number = "3",
volume = "115",
doi = "10.1093/oxfordjournals.jbchem.a124354",
pages = "422-428"
}

Poznanović, G., Martinović, V., Ivanović-Matić, S.,& Ševaljević, L.. (1994). Regions of the haptoglobin 5' flanking gene sequence show different binding affinities to nuclear matrix proteins during the acute phase response. in Journal of Biochemistry
Oxford, UK: Oxford University Press., 115(3), 422-428.
https://doi.org/10.1093/oxfordjournals.jbchem.a124354

Poznanović G, Martinović V, Ivanović-Matić S, Ševaljević L. Regions of the haptoglobin 5' flanking gene sequence show different binding affinities to nuclear matrix proteins during the acute phase response. in Journal of Biochemistry. 1994;115(3):422-428.
doi:10.1093/oxfordjournals.jbchem.a124354 .

Poznanović, Goran, Martinović, Vesna, Ivanović-Matić, Svetlana, Ševaljević, Ljiljana, "Regions of the haptoglobin 5' flanking gene sequence show different binding affinities to nuclear matrix proteins during the acute phase response" in Journal of Biochemistry, 115, no. 3 (1994):422-428,
https://doi.org/10.1093/oxfordjournals.jbchem.a124354 . .

TY  - JOUR
AU  - Poznanović, Goran
AU  - Martinović, Vesna
AU  - Ivanović-Matić, Svetlana
AU  - Ševaljević, Ljiljana
PY  - 1992
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/5644
AB  - Haptoglobin (Hp) is one of several plasma proteins ‚whose concentration increases aout three times during the acute phase response (1).  Its gene activity is controlled primarily by the action of transcriptional mechanisms (6).
In the work we studied the changes in the binding potential of the rat Hp gene sequences in the vicinity of its cis-element (-165/-147) (4) to nuclear matrix proteins during acute inflammation induced by turpentine.
PB  - Polish Academy of Sciences, Polish Histochemical and Cytochemical Society
T2  - Folia histochemica et cytobiologica
T1  - The association of 5' haptoglobin gene-flanking sequences with nuclear matrix proteins during the acute phase response
IS  - 4
VL  - 30
SP  - 151
EP  - 154
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_5644
ER  - 

@article{
author = "Poznanović, Goran and Martinović, Vesna and Ivanović-Matić, Svetlana and Ševaljević, Ljiljana",
year = "1992",
abstract = "Haptoglobin (Hp) is one of several plasma proteins ‚whose concentration increases aout three times during the acute phase response (1).  Its gene activity is controlled primarily by the action of transcriptional mechanisms (6).
In the work we studied the changes in the binding potential of the rat Hp gene sequences in the vicinity of its cis-element (-165/-147) (4) to nuclear matrix proteins during acute inflammation induced by turpentine.",
publisher = "Polish Academy of Sciences, Polish Histochemical and Cytochemical Society",
journal = "Folia histochemica et cytobiologica",
title = "The association of 5' haptoglobin gene-flanking sequences with nuclear matrix proteins during the acute phase response",
number = "4",
volume = "30",
pages = "151-154",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_5644"
}

Poznanović, G., Martinović, V., Ivanović-Matić, S.,& Ševaljević, L.. (1992). The association of 5' haptoglobin gene-flanking sequences with nuclear matrix proteins during the acute phase response. in Folia histochemica et cytobiologica
Polish Academy of Sciences, Polish Histochemical and Cytochemical Society., 30(4), 151-154.
https://hdl.handle.net/21.15107/rcub_ibiss_5644

Poznanović G, Martinović V, Ivanović-Matić S, Ševaljević L. The association of 5' haptoglobin gene-flanking sequences with nuclear matrix proteins during the acute phase response. in Folia histochemica et cytobiologica. 1992;30(4):151-154.
https://hdl.handle.net/21.15107/rcub_ibiss_5644 .

Poznanović, Goran, Martinović, Vesna, Ivanović-Matić, Svetlana, Ševaljević, Ljiljana, "The association of 5' haptoglobin gene-flanking sequences with nuclear matrix proteins during the acute phase response" in Folia histochemica et cytobiologica, 30, no. 4 (1992):151-154,
https://hdl.handle.net/21.15107/rcub_ibiss_5644 .