TY  - JOUR
AU  - Stanojković, Tatjana P
AU  - Kolundžija, Branka S
AU  - Ćirić, Ana
AU  - Soković, Marina
AU  - Nikolić, D
AU  - Kundaković, Tatjana D
PY  - 2013
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/1021
AB  - Methanolic extract of Satureja kitaibelii Wierzb. ex Heuff. (Lamiaceae) and its major compond rosmarinic acid possessed strong antimicrobial activity against tested bacteria and fungi, and antitumour activity against malignant cells, but without antiproliferative effect on healthy cell line MRC5. Minimal inhibitory concentration (MIC) of methanolic extract was ranged between 0.0125-1.25 mg/ml, while minimal bactericidal concentration (MBC) was of 0.2-5.0 mg/ml and fungicidal (MFC) was 0.15-2.5 mg/ml. The rosmarinic acid exhibited better antimicrobial activity then methanol extract. The most sensitive species to rosmarinic acid were Bacillus cereus and Candida kruzei, while Micrococcus flavus, Trichoderma viride and Aspergillus niger were the most resistant. The methanol extract exhibited strong activity against Fem-x human malignant melanoma cells with an IC50 39.66 +/- 2.71 mu g/ml, and moderate activity against other cancer cell lines (IC50 from 138.06 +/- 0.16 mu g/ml against estrogen-dependant breast cancer cell lines MDA-MB-361 to 173.15 +/- 0.02 against a human epithelial cervical cancer cells HeLa). Rosmarinic acid arrested G2/M phase cell cycle in Fem-x cells, against which both methanol extract and rosmarinic acid possessed the best cytotoxic activity.
T2  - Digest Journal of Nanomaterials and Biostructures
T1  - Cytotoxicity and Antimicrobial Activity of Satureja Kitaibelii Wierzb. Ex Heuff (Lamiaceae)
IS  - 2
VL  - 8
SP  - 139
EP  - 854
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_1021
ER  - 

@article{
author = "Stanojković, Tatjana P and Kolundžija, Branka S and Ćirić, Ana and Soković, Marina and Nikolić, D and Kundaković, Tatjana D",
year = "2013",
abstract = "Methanolic extract of Satureja kitaibelii Wierzb. ex Heuff. (Lamiaceae) and its major compond rosmarinic acid possessed strong antimicrobial activity against tested bacteria and fungi, and antitumour activity against malignant cells, but without antiproliferative effect on healthy cell line MRC5. Minimal inhibitory concentration (MIC) of methanolic extract was ranged between 0.0125-1.25 mg/ml, while minimal bactericidal concentration (MBC) was of 0.2-5.0 mg/ml and fungicidal (MFC) was 0.15-2.5 mg/ml. The rosmarinic acid exhibited better antimicrobial activity then methanol extract. The most sensitive species to rosmarinic acid were Bacillus cereus and Candida kruzei, while Micrococcus flavus, Trichoderma viride and Aspergillus niger were the most resistant. The methanol extract exhibited strong activity against Fem-x human malignant melanoma cells with an IC50 39.66 +/- 2.71 mu g/ml, and moderate activity against other cancer cell lines (IC50 from 138.06 +/- 0.16 mu g/ml against estrogen-dependant breast cancer cell lines MDA-MB-361 to 173.15 +/- 0.02 against a human epithelial cervical cancer cells HeLa). Rosmarinic acid arrested G2/M phase cell cycle in Fem-x cells, against which both methanol extract and rosmarinic acid possessed the best cytotoxic activity.",
journal = "Digest Journal of Nanomaterials and Biostructures",
title = "Cytotoxicity and Antimicrobial Activity of Satureja Kitaibelii Wierzb. Ex Heuff (Lamiaceae)",
number = "2",
volume = "8",
pages = "139-854",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_1021"
}

Stanojković, T. P., Kolundžija, B. S., Ćirić, A., Soković, M., Nikolić, D.,& Kundaković, T. D.. (2013). Cytotoxicity and Antimicrobial Activity of Satureja Kitaibelii Wierzb. Ex Heuff (Lamiaceae). in Digest Journal of Nanomaterials and Biostructures, 8(2), 139-854.
https://hdl.handle.net/21.15107/rcub_ibiss_1021

Stanojković TP, Kolundžija BS, Ćirić A, Soković M, Nikolić D, Kundaković TD. Cytotoxicity and Antimicrobial Activity of Satureja Kitaibelii Wierzb. Ex Heuff (Lamiaceae). in Digest Journal of Nanomaterials and Biostructures. 2013;8(2):139-854.
https://hdl.handle.net/21.15107/rcub_ibiss_1021 .

Stanojković, Tatjana P, Kolundžija, Branka S, Ćirić, Ana, Soković, Marina, Nikolić, D, Kundaković, Tatjana D, "Cytotoxicity and Antimicrobial Activity of Satureja Kitaibelii Wierzb. Ex Heuff (Lamiaceae)" in Digest Journal of Nanomaterials and Biostructures, 8, no. 2 (2013):139-854,
https://hdl.handle.net/21.15107/rcub_ibiss_1021 .