TY  - JOUR
AU  - Macanović, Biljana
AU  - Vučetić, Milica
AU  - Janković, Aleksandra
AU  - Stančić, Ana
AU  - Buzadžić, Biljana J.
AU  - Garalejić, Eliana
AU  - Korać, Aleksandra
AU  - Korać, Bato
AU  - Otašević, Vesna
PY  - 2015
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/2090
AB  - Background. Semen analysis is the cornerstone in the evaluation of male
   (in) fertility. However, there are men with normal semen tests but with
   impaired fertilizing ability, as well as fertile men with poor sperm
   characteristics. Thus, there is rising interest to find novel parameters
   that will help to predict and define the functional capacity of
   spermatozoa. Methods. We examined whether there is a correlation between
   semen parameters (count, progressive motility, and morphology) and
   protein expression/activity of antioxidative defense enzymes in seminal
   plasma from 10 normospermic subjects. Results. Sperm progressive
   motility was in positive correlation with seminal plasma protein
   expression of both superoxide dismutase (SOD) isoforms (MnSOD and
   CuZnSOD) and catalase. Also, positive correlation was observed between
   sperm count and MnSOD protein expression, as well as between sperm
   morphology and protein expression of catalase in seminal plasma. In
   contrast, protein expression of glutathione peroxidase was not in
   correlation with any sperm parameter, while its activity negatively
   correlated with sperm morphology and motility. Conclusions. These data
   suggest that evaluation of protein expression of antioxidative defense
   enzymes in seminal plasma might be of importance in the evaluation of
   male fertility status and that could be used as an additional biomarker
   along with classic semen analysis in assessment of semen quality.
T2  - Disease Markers
T1  - Correlation between Sperm Parameters and Protein Expression of
 Antioxidative Defense Enzymes in Seminal Plasma: A Pilot Study
IS  - 436236
DO  - 10.1155/2015/436236
ER  - 

@article{
author = "Macanović, Biljana and Vučetić, Milica and Janković, Aleksandra and Stančić, Ana and Buzadžić, Biljana J. and Garalejić, Eliana and Korać, Aleksandra and Korać, Bato and Otašević, Vesna",
year = "2015",
abstract = "Background. Semen analysis is the cornerstone in the evaluation of male
   (in) fertility. However, there are men with normal semen tests but with
   impaired fertilizing ability, as well as fertile men with poor sperm
   characteristics. Thus, there is rising interest to find novel parameters
   that will help to predict and define the functional capacity of
   spermatozoa. Methods. We examined whether there is a correlation between
   semen parameters (count, progressive motility, and morphology) and
   protein expression/activity of antioxidative defense enzymes in seminal
   plasma from 10 normospermic subjects. Results. Sperm progressive
   motility was in positive correlation with seminal plasma protein
   expression of both superoxide dismutase (SOD) isoforms (MnSOD and
   CuZnSOD) and catalase. Also, positive correlation was observed between
   sperm count and MnSOD protein expression, as well as between sperm
   morphology and protein expression of catalase in seminal plasma. In
   contrast, protein expression of glutathione peroxidase was not in
   correlation with any sperm parameter, while its activity negatively
   correlated with sperm morphology and motility. Conclusions. These data
   suggest that evaluation of protein expression of antioxidative defense
   enzymes in seminal plasma might be of importance in the evaluation of
   male fertility status and that could be used as an additional biomarker
   along with classic semen analysis in assessment of semen quality.",
journal = "Disease Markers",
title = "Correlation between Sperm Parameters and Protein Expression of
 Antioxidative Defense Enzymes in Seminal Plasma: A Pilot Study",
number = "436236",
doi = "10.1155/2015/436236"
}

Macanović, B., Vučetić, M., Janković, A., Stančić, A., Buzadžić, B. J., Garalejić, E., Korać, A., Korać, B.,& Otašević, V.. (2015). Correlation between Sperm Parameters and Protein Expression of
 Antioxidative Defense Enzymes in Seminal Plasma: A Pilot Study. in Disease Markers(436236).
https://doi.org/10.1155/2015/436236

Macanović B, Vučetić M, Janković A, Stančić A, Buzadžić BJ, Garalejić E, Korać A, Korać B, Otašević V. Correlation between Sperm Parameters and Protein Expression of
 Antioxidative Defense Enzymes in Seminal Plasma: A Pilot Study. in Disease Markers. 2015;(436236).
doi:10.1155/2015/436236 .

Macanović, Biljana, Vučetić, Milica, Janković, Aleksandra, Stančić, Ana, Buzadžić, Biljana J., Garalejić, Eliana, Korać, Aleksandra, Korać, Bato, Otašević, Vesna, "Correlation between Sperm Parameters and Protein Expression of
 Antioxidative Defense Enzymes in Seminal Plasma: A Pilot Study" in Disease Markers, no. 436236 (2015),
https://doi.org/10.1155/2015/436236 . .