Identification, measurement and development of the cognitive and emotional competences important for a Europe-oriented society

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Identification, measurement and development of the cognitive and emotional competences important for a Europe-oriented society (en)
Идентификација, мерење и развој когнитивних и емоционалних компетенција важних друштву оријентисаном на европске интеграције (sr)
Identifikacija, merenje i razvoj kognitivnih i emocionalnih kompetencija važnih društvu orijentisanom na evropske integracije (sr_RS)
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Publications

PTSD and depressive symptoms are linked to DHEAS via personality.

Savić, Danka; Knežević, Goran; Matić, Gordana; Damjanović, Svetozar

(2018) 

TY  - JOUR
AU  - Savić, Danka
AU  - Knežević, Goran
AU  - Matić, Gordana
AU  - Damjanović, Svetozar
PY  - 2018
UR  - http://www.psyneuen-journal.com/article/S0306-4530(18)30088-X/fulltext
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/3034
AB  - BACKGROUND Research results on dehydroepiandrosterone sulfate ester (DHEAS) in post-traumatic stress disorder (PTSD) are inconsistent. We hypothesized that personality traits could be the confounders of DHEAS levels and disease symptoms, which could in part explain the discrepancy in findings. METHOD This study was a part of a broader project in which simultaneous psychological and biological investigations were carried out in hospital conditions. 380 male subjects were categorized in four groups: A) current PTSD (n = 132), B) lifetime PTSD (n = 66), C) trauma controls (n = 101), and D) healthy controls (n = 81), matched by age. RESULTS The level of DHEAS is significantly lower in the current PTSD group than in trauma controls. All groups significantly differ in personality traits Disintegration and Neuroticism (current PTSD group having the highest scores). DHEAS is related to both PTSD and depressive symptoms; however, Structural Equation Model (SEM) shows that the relations are indirect, realized via their confounder - personality trait Disintegration. CONCLUSIONS According to our project results, DHEAS is the second putative biomarker for trauma-related disorders that fails to fulfil this expectation. It appears to be more directly related to personality than to the disease symptoms (the first one being basal cortisol). Our data promote personality as a biologically based construct with seemingly important role in understanding the mental health status.
T2  - Psychoneuroendocrinology
T1  - PTSD and depressive symptoms are linked to DHEAS via personality.
VL  - 92
DO  - 10.1016/j.psyneuen.2018.03.017
SP  - 29
EP  - 33
ER  - 
@article{
author = "Savić, Danka and Knežević, Goran and Matić, Gordana and Damjanović, Svetozar",
year = "2018",
abstract = "BACKGROUND Research results on dehydroepiandrosterone sulfate ester (DHEAS) in post-traumatic stress disorder (PTSD) are inconsistent. We hypothesized that personality traits could be the confounders of DHEAS levels and disease symptoms, which could in part explain the discrepancy in findings. METHOD This study was a part of a broader project in which simultaneous psychological and biological investigations were carried out in hospital conditions. 380 male subjects were categorized in four groups: A) current PTSD (n = 132), B) lifetime PTSD (n = 66), C) trauma controls (n = 101), and D) healthy controls (n = 81), matched by age. RESULTS The level of DHEAS is significantly lower in the current PTSD group than in trauma controls. All groups significantly differ in personality traits Disintegration and Neuroticism (current PTSD group having the highest scores). DHEAS is related to both PTSD and depressive symptoms; however, Structural Equation Model (SEM) shows that the relations are indirect, realized via their confounder - personality trait Disintegration. CONCLUSIONS According to our project results, DHEAS is the second putative biomarker for trauma-related disorders that fails to fulfil this expectation. It appears to be more directly related to personality than to the disease symptoms (the first one being basal cortisol). Our data promote personality as a biologically based construct with seemingly important role in understanding the mental health status.",
journal = "Psychoneuroendocrinology",
title = "PTSD and depressive symptoms are linked to DHEAS via personality.",
volume = "92",
doi = "10.1016/j.psyneuen.2018.03.017",
pages = "29-33"
}
Savić, D., Knežević, G., Matić, G.,& Damjanović, S.. (2018). PTSD and depressive symptoms are linked to DHEAS via personality.. in Psychoneuroendocrinology, 92, 29-33.
https://doi.org/10.1016/j.psyneuen.2018.03.017
Savić D, Knežević G, Matić G, Damjanović S. PTSD and depressive symptoms are linked to DHEAS via personality.. in Psychoneuroendocrinology. 2018;92:29-33.
doi:10.1016/j.psyneuen.2018.03.017 .
Savić, Danka, Knežević, Goran, Matić, Gordana, Damjanović, Svetozar, "PTSD and depressive symptoms are linked to DHEAS via personality." in Psychoneuroendocrinology, 92 (2018):29-33,
https://doi.org/10.1016/j.psyneuen.2018.03.017 . .
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