Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200358 (BioSense Institute)

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Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200358 (BioSense Institute) (en)
Ministarstvo prosvete, nauke i tehnološkog razvoja Republike Srbije, Ugovor br. 451-03-68/2020-14/200358 (BioSense institut) (sr_RS)
Министарство просвете, науке и технолошког развоја Републике Србије, Уговор бр. 451-03-68/2020-14/200358 (BioSense институт) (sr)
Authors

Publications

Melissopalynology analysis, determination of physicochemical parameters, sugars and phenolics in Maltese honey collected in different seasons

Bugeja Douglas, Adrian; Nešović, Milica; Šikoparija, Branko; Radišić, Predrag; Tosti, Tomislav; Trifković, Jelena; Russi, Luigi; Attard, Everaldo; Tešić, Živoslav; Gašić, Uroš

(Belgrade: Serbian Chemical Society, 2022)

TY  - JOUR
AU  - Bugeja Douglas, Adrian
AU  - Nešović, Milica
AU  - Šikoparija, Branko
AU  - Radišić, Predrag
AU  - Tosti, Tomislav
AU  - Trifković, Jelena
AU  - Russi, Luigi
AU  - Attard, Everaldo
AU  - Tešić, Živoslav
AU  - Gašić, Uroš
PY  - 2022
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/5665
AB  - Malta, a country renowned for its honey, has not been extensively mentioned in studies based on honey. In addition to many parameters, the collection period affects honey quality, precisely due to the different floral composition that exists during a certain season. Therefore, the significance of this study refers to the provision of data on honey from Malta collected during the autumn, spring, and summer seasons. Melissopalynological analysis, determination of physicochemical parameters, and the use of analytical chromatographic methods enabled detailed analysis of this honey. Principal component analysis (PCA) provided the differentiation of Maltese honey depending on the harvest season. Lotus pollen, followed by Eucalyptus, predominated in all honey samples. Characteristic compounds for summer honey were pinocembrin, galangin, kaempferol, chrysin, p-hydroxybenzoic acid, vanillic acid and maltotriose, while quercetin 3-O-galactoside, ferulic acid, ellagic acid, protocatechuic acid, luteolin 7-O-glucoside and melibiose were specific for autumn honey. A higher amount of p-coumaric acid, genistein, catechin, as well as the content of many sugars were found in spring samples. To the best of our knowledge, this is the first scientific work dealing with a detailed chemical analysis of Maltese honey.
PB  - Belgrade: Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - Melissopalynology analysis, determination of physicochemical parameters, sugars and phenolics in Maltese honey collected in different seasons
IS  - 9
VL  - 87
DO  - 10.2298/JSC211214033B
SP  - 983
EP  - 995
ER  - 
@article{
author = "Bugeja Douglas, Adrian and Nešović, Milica and Šikoparija, Branko and Radišić, Predrag and Tosti, Tomislav and Trifković, Jelena and Russi, Luigi and Attard, Everaldo and Tešić, Živoslav and Gašić, Uroš",
year = "2022",
abstract = "Malta, a country renowned for its honey, has not been extensively mentioned in studies based on honey. In addition to many parameters, the collection period affects honey quality, precisely due to the different floral composition that exists during a certain season. Therefore, the significance of this study refers to the provision of data on honey from Malta collected during the autumn, spring, and summer seasons. Melissopalynological analysis, determination of physicochemical parameters, and the use of analytical chromatographic methods enabled detailed analysis of this honey. Principal component analysis (PCA) provided the differentiation of Maltese honey depending on the harvest season. Lotus pollen, followed by Eucalyptus, predominated in all honey samples. Characteristic compounds for summer honey were pinocembrin, galangin, kaempferol, chrysin, p-hydroxybenzoic acid, vanillic acid and maltotriose, while quercetin 3-O-galactoside, ferulic acid, ellagic acid, protocatechuic acid, luteolin 7-O-glucoside and melibiose were specific for autumn honey. A higher amount of p-coumaric acid, genistein, catechin, as well as the content of many sugars were found in spring samples. To the best of our knowledge, this is the first scientific work dealing with a detailed chemical analysis of Maltese honey.",
publisher = "Belgrade: Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "Melissopalynology analysis, determination of physicochemical parameters, sugars and phenolics in Maltese honey collected in different seasons",
number = "9",
volume = "87",
doi = "10.2298/JSC211214033B",
pages = "983-995"
}
Bugeja Douglas, A., Nešović, M., Šikoparija, B., Radišić, P., Tosti, T., Trifković, J., Russi, L., Attard, E., Tešić, Ž.,& Gašić, U.. (2022). Melissopalynology analysis, determination of physicochemical parameters, sugars and phenolics in Maltese honey collected in different seasons. in Journal of the Serbian Chemical Society
Belgrade: Serbian Chemical Society., 87(9), 983-995.
https://doi.org/10.2298/JSC211214033B
Bugeja Douglas A, Nešović M, Šikoparija B, Radišić P, Tosti T, Trifković J, Russi L, Attard E, Tešić Ž, Gašić U. Melissopalynology analysis, determination of physicochemical parameters, sugars and phenolics in Maltese honey collected in different seasons. in Journal of the Serbian Chemical Society. 2022;87(9):983-995.
doi:10.2298/JSC211214033B .
Bugeja Douglas, Adrian, Nešović, Milica, Šikoparija, Branko, Radišić, Predrag, Tosti, Tomislav, Trifković, Jelena, Russi, Luigi, Attard, Everaldo, Tešić, Živoslav, Gašić, Uroš, "Melissopalynology analysis, determination of physicochemical parameters, sugars and phenolics in Maltese honey collected in different seasons" in Journal of the Serbian Chemical Society, 87, no. 9 (2022):983-995,
https://doi.org/10.2298/JSC211214033B . .
3
2

Cell adhesion characteristics of polyurethane-mesoporous silica nanoparticle composite materials

Pergal, Marija; Brkljačić, Jelena; Tovilović-Kovačević, Gordana; Špirkova, Milena; Kodranov, Igor; Manojlović, Dragan; Knežević, Nenad

(Belgrade: Society of Physical Chemists of Serbia, 2021)

TY  - CONF
AU  - Pergal, Marija
AU  - Brkljačić, Jelena
AU  - Tovilović-Kovačević, Gordana
AU  - Špirkova, Milena
AU  - Kodranov, Igor
AU  - Manojlović, Dragan
AU  - Knežević, Nenad
PY  - 2021
UR  - http://www.socphyschemserb.org/sr/publikacije/
UR  - http://radar.ibiss.bg.ac.rs/handle/123456789/5732
AB  - Surface characteristics and biocompatibility of new nanocomposites based on polyurethane network
and mesoporous silica nanoparticles (PUMSNs) were investigated. Surface topography and
roughness coefficient were studied by AFM. Biocompatibility with endothelial cells and cytotoxicity
of the PUNs were assessed using MTT (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl-tetrazolium
bromide) and cell adhesion assays. The addition of MSNs into polyurethane network led to
improvement of surface properties, as well as exhibited promising characteristics regarding adhesion
of cells, toward potential application in coating for medical devices.
PB  - Belgrade: Society of Physical Chemists of Serbia
C3  - Proceedings:the Conference is dedicated to the 30th Anniversary of the founding of the Society of Physical Chemists of Serbia and 100th Anniversary of Bray-Liebhafsky reaction: Physical Chemistry 2021. Vol. 2; 2021 Sep 20-24; Belgrade, Serbia
T1  - Cell adhesion characteristics of polyurethane-mesoporous silica nanoparticle composite materials
SP  - 480
EP  - 482
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_5732
ER  - 
@conference{
author = "Pergal, Marija and Brkljačić, Jelena and Tovilović-Kovačević, Gordana and Špirkova, Milena and Kodranov, Igor and Manojlović, Dragan and Knežević, Nenad",
year = "2021",
abstract = "Surface characteristics and biocompatibility of new nanocomposites based on polyurethane network
and mesoporous silica nanoparticles (PUMSNs) were investigated. Surface topography and
roughness coefficient were studied by AFM. Biocompatibility with endothelial cells and cytotoxicity
of the PUNs were assessed using MTT (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl-tetrazolium
bromide) and cell adhesion assays. The addition of MSNs into polyurethane network led to
improvement of surface properties, as well as exhibited promising characteristics regarding adhesion
of cells, toward potential application in coating for medical devices.",
publisher = "Belgrade: Society of Physical Chemists of Serbia",
journal = "Proceedings:the Conference is dedicated to the 30th Anniversary of the founding of the Society of Physical Chemists of Serbia and 100th Anniversary of Bray-Liebhafsky reaction: Physical Chemistry 2021. Vol. 2; 2021 Sep 20-24; Belgrade, Serbia",
title = "Cell adhesion characteristics of polyurethane-mesoporous silica nanoparticle composite materials",
pages = "480-482",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_5732"
}
Pergal, M., Brkljačić, J., Tovilović-Kovačević, G., Špirkova, M., Kodranov, I., Manojlović, D.,& Knežević, N.. (2021). Cell adhesion characteristics of polyurethane-mesoporous silica nanoparticle composite materials. in Proceedings:the Conference is dedicated to the 30th Anniversary of the founding of the Society of Physical Chemists of Serbia and 100th Anniversary of Bray-Liebhafsky reaction: Physical Chemistry 2021. Vol. 2; 2021 Sep 20-24; Belgrade, Serbia
Belgrade: Society of Physical Chemists of Serbia., 480-482.
https://hdl.handle.net/21.15107/rcub_ibiss_5732
Pergal M, Brkljačić J, Tovilović-Kovačević G, Špirkova M, Kodranov I, Manojlović D, Knežević N. Cell adhesion characteristics of polyurethane-mesoporous silica nanoparticle composite materials. in Proceedings:the Conference is dedicated to the 30th Anniversary of the founding of the Society of Physical Chemists of Serbia and 100th Anniversary of Bray-Liebhafsky reaction: Physical Chemistry 2021. Vol. 2; 2021 Sep 20-24; Belgrade, Serbia. 2021;:480-482.
https://hdl.handle.net/21.15107/rcub_ibiss_5732 .
Pergal, Marija, Brkljačić, Jelena, Tovilović-Kovačević, Gordana, Špirkova, Milena, Kodranov, Igor, Manojlović, Dragan, Knežević, Nenad, "Cell adhesion characteristics of polyurethane-mesoporous silica nanoparticle composite materials" in Proceedings:the Conference is dedicated to the 30th Anniversary of the founding of the Society of Physical Chemists of Serbia and 100th Anniversary of Bray-Liebhafsky reaction: Physical Chemistry 2021. Vol. 2; 2021 Sep 20-24; Belgrade, Serbia (2021):480-482,
https://hdl.handle.net/21.15107/rcub_ibiss_5732 .

Effect of mesoporous silica nanoparticles on the properties of polyurethane network composites

Pergal, Marija V.; Brkljačić, Jelena; Tovilović-Kovačević, Gordana; Špírkova, Milena; Kodranov, Igor D.; Manojlović, Dragan D.; Ostojić, Sanja; Knežević, Nikola Ž.

(Elsevier, 2021)

TY  - JOUR
AU  - Pergal, Marija V.
AU  - Brkljačić, Jelena
AU  - Tovilović-Kovačević, Gordana
AU  - Špírkova, Milena
AU  - Kodranov, Igor D.
AU  - Manojlović, Dragan D.
AU  - Ostojić, Sanja
AU  - Knežević, Nikola Ž.
PY  - 2021
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/4161
AB  - Novel polyurethane nanocomposite (PUN) materials containing different surface-functionalized mesoporous silica nanoparticles (MSNs) were prepared by in situ polymerization methodology. Polyurethane network was formed from poly (dimethylsiloxane)-based macrodiol (PDMS), 4, 4′ -methylenediphenyldiisocyanate (MDI), and hyperbranched polyester of the second pseudo-generation (BH-20; used as crosslinking agent). PU and PU/MSN nanocomposites contained equal ratios of soft PDMS and hard MDI-BH-20 segments. Non-functionalized and surface-functionalized (with 3-(trihydroxysilyl) propyl methylphosphonate (FOMSN) and 2-[methoxy (polyethyleneoxy) 6-9propyl] trimethoxysilane (PEGMSN)) MSNs were used as the nanofillers at a concentration of 1 wt%. Prepared materials were characterized by Fourier transform infrared (FTIR) spectroscopy, atomic force microscopy (AFM), scanning electron microscopy (SEM), thermogravimetric analysis (TGA), differential scanning calorimetry (DSC), dynamic mechanical thermal analyses (DMTA), nanoindentation, equilibrium swelling and water absorption measurements. Characteristics of the prepared PUNs when in contact with a biological environment were assessed through testing their biocompatibility, protein adsorption and adhesion of endothelial cells. The favourable influence of MSNs on the physico-chemical and biological characteristics of these novel PUN materials was identified, which evidences their vast applicability potential as coatings for medical devices and implants.
PB  - Elsevier
T2  - Progress in Organic Coatings
T1  - Effect of mesoporous silica nanoparticles on the properties of polyurethane network composites
VL  - 151
DO  - 10.1016/j.porgcoat.2020.106049
SP  - 106049
ER  - 
@article{
author = "Pergal, Marija V. and Brkljačić, Jelena and Tovilović-Kovačević, Gordana and Špírkova, Milena and Kodranov, Igor D. and Manojlović, Dragan D. and Ostojić, Sanja and Knežević, Nikola Ž.",
year = "2021",
abstract = "Novel polyurethane nanocomposite (PUN) materials containing different surface-functionalized mesoporous silica nanoparticles (MSNs) were prepared by in situ polymerization methodology. Polyurethane network was formed from poly (dimethylsiloxane)-based macrodiol (PDMS), 4, 4′ -methylenediphenyldiisocyanate (MDI), and hyperbranched polyester of the second pseudo-generation (BH-20; used as crosslinking agent). PU and PU/MSN nanocomposites contained equal ratios of soft PDMS and hard MDI-BH-20 segments. Non-functionalized and surface-functionalized (with 3-(trihydroxysilyl) propyl methylphosphonate (FOMSN) and 2-[methoxy (polyethyleneoxy) 6-9propyl] trimethoxysilane (PEGMSN)) MSNs were used as the nanofillers at a concentration of 1 wt%. Prepared materials were characterized by Fourier transform infrared (FTIR) spectroscopy, atomic force microscopy (AFM), scanning electron microscopy (SEM), thermogravimetric analysis (TGA), differential scanning calorimetry (DSC), dynamic mechanical thermal analyses (DMTA), nanoindentation, equilibrium swelling and water absorption measurements. Characteristics of the prepared PUNs when in contact with a biological environment were assessed through testing their biocompatibility, protein adsorption and adhesion of endothelial cells. The favourable influence of MSNs on the physico-chemical and biological characteristics of these novel PUN materials was identified, which evidences their vast applicability potential as coatings for medical devices and implants.",
publisher = "Elsevier",
journal = "Progress in Organic Coatings",
title = "Effect of mesoporous silica nanoparticles on the properties of polyurethane network composites",
volume = "151",
doi = "10.1016/j.porgcoat.2020.106049",
pages = "106049"
}
Pergal, M. V., Brkljačić, J., Tovilović-Kovačević, G., Špírkova, M., Kodranov, I. D., Manojlović, D. D., Ostojić, S.,& Knežević, N. Ž.. (2021). Effect of mesoporous silica nanoparticles on the properties of polyurethane network composites. in Progress in Organic Coatings
Elsevier., 151, 106049.
https://doi.org/10.1016/j.porgcoat.2020.106049
Pergal MV, Brkljačić J, Tovilović-Kovačević G, Špírkova M, Kodranov ID, Manojlović DD, Ostojić S, Knežević NŽ. Effect of mesoporous silica nanoparticles on the properties of polyurethane network composites. in Progress in Organic Coatings. 2021;151:106049.
doi:10.1016/j.porgcoat.2020.106049 .
Pergal, Marija V., Brkljačić, Jelena, Tovilović-Kovačević, Gordana, Špírkova, Milena, Kodranov, Igor D., Manojlović, Dragan D., Ostojić, Sanja, Knežević, Nikola Ž., "Effect of mesoporous silica nanoparticles on the properties of polyurethane network composites" in Progress in Organic Coatings, 151 (2021):106049,
https://doi.org/10.1016/j.porgcoat.2020.106049 . .
6
6

Polyphenolic profile of buckwheat honey, nectar and pollen

Nešović, Milica; Gašić, Uroš; Tosti, Tomislav; Horvacki, Nikola; Šikoparija, Branko; Nedić, Nebojša; Blagojević, Stevan; Ignjatović, Ljubiša; Tešić, Živoslav

(Royal Society of Chemistry, 2020)

TY  - JOUR
AU  - Nešović, Milica
AU  - Gašić, Uroš
AU  - Tosti, Tomislav
AU  - Horvacki, Nikola
AU  - Šikoparija, Branko
AU  - Nedić, Nebojša
AU  - Blagojević, Stevan
AU  - Ignjatović, Ljubiša
AU  - Tešić, Živoslav
PY  - 2020
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/4058
AB  - A focus of research in recent years is the comparison of honey as the final product of bees with pollen and nectar of the plant from which the honey originates, as the main food source for bees. Buckwheat honey is recognized as a nutritionally valuable product, which provides a scientifically proven health benefit and is confirmed as a functional food. The quality of this type of honey is attributed to high levels of phytochemicals in buckwheat. The purpose of this study was the examination of similarity between buckwheat honey and buckwheat nectar and pollen, as well as simultaneous investigation of their chemical profiles and the origin of the honey. The phenolic profile of buckwheat pollen showed a lower number of flavonoids and phenolic acids than those of nectar and honey samples, but confirmed the presence of the most characteristic polyphenols derived from the buckwheat plant. The notable difference was found to be the presence of (epi)catechin units, its galloylated derivatives and procyanidin dimers, which were not present in honey. Honey polyphenols displayed a pronounced correlation with those of nectar, but not with those of pollen. Finally, by comparing the polyphenolic profiles of honey, nectar and pollen sharing the same geographical origin, new data could be provided for a potential assessment of the botanical origin of buckwheat honey.
PB  - Royal Society of Chemistry
T2  - Royal Society Open Science
T1  - Polyphenolic profile of buckwheat honey, nectar and pollen
IS  - 12
VL  - 7
DO  - 10.1098/rsos.201576
SP  - 201576
ER  - 
@article{
author = "Nešović, Milica and Gašić, Uroš and Tosti, Tomislav and Horvacki, Nikola and Šikoparija, Branko and Nedić, Nebojša and Blagojević, Stevan and Ignjatović, Ljubiša and Tešić, Živoslav",
year = "2020",
abstract = "A focus of research in recent years is the comparison of honey as the final product of bees with pollen and nectar of the plant from which the honey originates, as the main food source for bees. Buckwheat honey is recognized as a nutritionally valuable product, which provides a scientifically proven health benefit and is confirmed as a functional food. The quality of this type of honey is attributed to high levels of phytochemicals in buckwheat. The purpose of this study was the examination of similarity between buckwheat honey and buckwheat nectar and pollen, as well as simultaneous investigation of their chemical profiles and the origin of the honey. The phenolic profile of buckwheat pollen showed a lower number of flavonoids and phenolic acids than those of nectar and honey samples, but confirmed the presence of the most characteristic polyphenols derived from the buckwheat plant. The notable difference was found to be the presence of (epi)catechin units, its galloylated derivatives and procyanidin dimers, which were not present in honey. Honey polyphenols displayed a pronounced correlation with those of nectar, but not with those of pollen. Finally, by comparing the polyphenolic profiles of honey, nectar and pollen sharing the same geographical origin, new data could be provided for a potential assessment of the botanical origin of buckwheat honey.",
publisher = "Royal Society of Chemistry",
journal = "Royal Society Open Science",
title = "Polyphenolic profile of buckwheat honey, nectar and pollen",
number = "12",
volume = "7",
doi = "10.1098/rsos.201576",
pages = "201576"
}
Nešović, M., Gašić, U., Tosti, T., Horvacki, N., Šikoparija, B., Nedić, N., Blagojević, S., Ignjatović, L.,& Tešić, Ž.. (2020). Polyphenolic profile of buckwheat honey, nectar and pollen. in Royal Society Open Science
Royal Society of Chemistry., 7(12), 201576.
https://doi.org/10.1098/rsos.201576
Nešović M, Gašić U, Tosti T, Horvacki N, Šikoparija B, Nedić N, Blagojević S, Ignjatović L, Tešić Ž. Polyphenolic profile of buckwheat honey, nectar and pollen. in Royal Society Open Science. 2020;7(12):201576.
doi:10.1098/rsos.201576 .
Nešović, Milica, Gašić, Uroš, Tosti, Tomislav, Horvacki, Nikola, Šikoparija, Branko, Nedić, Nebojša, Blagojević, Stevan, Ignjatović, Ljubiša, Tešić, Živoslav, "Polyphenolic profile of buckwheat honey, nectar and pollen" in Royal Society Open Science, 7, no. 12 (2020):201576,
https://doi.org/10.1098/rsos.201576 . .
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