TY  - JOUR
AU  - Sparks, Jackson T.
AU  - Bohbot, Jonathan D.
AU  - Ristić, Mihailo
AU  - Mišić, Danijela
AU  - Skorić, Marijana
AU  - Mattoo, Autar
AU  - Dickens, Joseph C.
PY  - 2017
UR  - https://academic.oup.com/jme/article-lookup/doi/10.1093/jme/tjx059
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/2808
AB  - Nepeta essential oil (Neo; catnip) and its major component, nepetalactone, have long been known to repel insects including mosquitoes. However, the neural mechanisms through which these repellents are detected by mosquitoes, including the yellow fever mosquito Aedes aegypti (L.), an important vector of Zika virus, were poorly understood. Here we show that Neo volatiles activate olfactory receptor neurons within the basiconic sensilla on the maxillary palps of female Ae. aegypti. A gustatory receptor neuron sensitive to the feeding deterrent quinine and housed within sensilla on the labella of females was activated by both Neo and nepetalactone. Activity of a second gustatory receptor neuron sensitive to the feeding stimulant sucrose was suppressed by both repellents. Our results provide neural pathways for the reported spatial repellency and feeding deterrence of these repell ents. A better understanding of the neural input through which female mosquitoes make decisions to feed will facilitate design of new repellents and management strategies involving their use.
T2  - Journal of Medical Entomology
T1  - Chemosensory Responses to the Repellent Nepeta Essential Oil and Its Major Component Nepetalactone by Aedes aegypti (Diptera: Culicidae), a Vector of Zika Virus
DO  - 10.1093/jme/tjx059
ER  - 

@article{
author = "Sparks, Jackson T. and Bohbot, Jonathan D. and Ristić, Mihailo and Mišić, Danijela and Skorić, Marijana and Mattoo, Autar and Dickens, Joseph C.",
year = "2017",
abstract = "Nepeta essential oil (Neo; catnip) and its major component, nepetalactone, have long been known to repel insects including mosquitoes. However, the neural mechanisms through which these repellents are detected by mosquitoes, including the yellow fever mosquito Aedes aegypti (L.), an important vector of Zika virus, were poorly understood. Here we show that Neo volatiles activate olfactory receptor neurons within the basiconic sensilla on the maxillary palps of female Ae. aegypti. A gustatory receptor neuron sensitive to the feeding deterrent quinine and housed within sensilla on the labella of females was activated by both Neo and nepetalactone. Activity of a second gustatory receptor neuron sensitive to the feeding stimulant sucrose was suppressed by both repellents. Our results provide neural pathways for the reported spatial repellency and feeding deterrence of these repell ents. A better understanding of the neural input through which female mosquitoes make decisions to feed will facilitate design of new repellents and management strategies involving their use.",
journal = "Journal of Medical Entomology",
title = "Chemosensory Responses to the Repellent Nepeta Essential Oil and Its Major Component Nepetalactone by Aedes aegypti (Diptera: Culicidae), a Vector of Zika Virus",
doi = "10.1093/jme/tjx059"
}

Sparks, J. T., Bohbot, J. D., Ristić, M., Mišić, D., Skorić, M., Mattoo, A.,& Dickens, J. C.. (2017). Chemosensory Responses to the Repellent Nepeta Essential Oil and Its Major Component Nepetalactone by Aedes aegypti (Diptera: Culicidae), a Vector of Zika Virus. in Journal of Medical Entomology.
https://doi.org/10.1093/jme/tjx059

Sparks JT, Bohbot JD, Ristić M, Mišić D, Skorić M, Mattoo A, Dickens JC. Chemosensory Responses to the Repellent Nepeta Essential Oil and Its Major Component Nepetalactone by Aedes aegypti (Diptera: Culicidae), a Vector of Zika Virus. in Journal of Medical Entomology. 2017;.
doi:10.1093/jme/tjx059 .

Sparks, Jackson T., Bohbot, Jonathan D., Ristić, Mihailo, Mišić, Danijela, Skorić, Marijana, Mattoo, Autar, Dickens, Joseph C., "Chemosensory Responses to the Repellent Nepeta Essential Oil and Its Major Component Nepetalactone by Aedes aegypti (Diptera: Culicidae), a Vector of Zika Virus" in Journal of Medical Entomology (2017),
https://doi.org/10.1093/jme/tjx059 . .

TY  - JOUR
AU  - Sparks, Jackson T.
AU  - Bohbot, Jonathan D.
AU  - Ristić, Mihailo
AU  - Mišić, Danijela
AU  - Skorić, Marijana
AU  - Mattoo, Autar
AU  - Dickens, Joseph C.
PY  - 2017
UR  - https://academic.oup.com/jme/article-lookup/doi/10.1093/jme/tjx059
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/2805
AB  - Nepeta essential oil (Neo; catnip) and its major component, nepetalactone, have long been known to repel insects including mosquitoes. However, the neural mechanisms through which these repellents are detected by mosquitoes, including the yellow fever mosquito Aedes aegypti (L.), an important vector of Zika virus, were poorly understood. Here we show that Neo volatiles activate olfactory receptor neurons within the basiconic sensilla on the maxillary palps of female Ae. aegypti. A gustatory receptor neuron sensitive to the feeding deterrent quinine and housed within sensilla on the labella of females was activated by both Neo and nepetalactone. Activity of a second gustatory receptor neuron sensitive to the feeding stimulant sucrose was suppressed by both repellents. Our results provide neural pathways for the reported spatial repellency and feeding deterrence of these repell ents. A better understanding of the neural input through which female mosquitoes make decisions to feed will facilitate design of new repellents and management strategies involving their use.
T2  - Journal of Medical Entomology
T1  - Chemosensory Responses to the Repellent Nepeta Essential Oil and Its Major Component Nepetalactone by Aedes aegypti (Diptera: Culicidae), a Vector of Zika Virus
IS  - 4
VL  - 54
DO  - 10.1093/jme/tjx059
SP  - 957
EP  - 963
ER  - 

@article{
author = "Sparks, Jackson T. and Bohbot, Jonathan D. and Ristić, Mihailo and Mišić, Danijela and Skorić, Marijana and Mattoo, Autar and Dickens, Joseph C.",
year = "2017",
abstract = "Nepeta essential oil (Neo; catnip) and its major component, nepetalactone, have long been known to repel insects including mosquitoes. However, the neural mechanisms through which these repellents are detected by mosquitoes, including the yellow fever mosquito Aedes aegypti (L.), an important vector of Zika virus, were poorly understood. Here we show that Neo volatiles activate olfactory receptor neurons within the basiconic sensilla on the maxillary palps of female Ae. aegypti. A gustatory receptor neuron sensitive to the feeding deterrent quinine and housed within sensilla on the labella of females was activated by both Neo and nepetalactone. Activity of a second gustatory receptor neuron sensitive to the feeding stimulant sucrose was suppressed by both repellents. Our results provide neural pathways for the reported spatial repellency and feeding deterrence of these repell ents. A better understanding of the neural input through which female mosquitoes make decisions to feed will facilitate design of new repellents and management strategies involving their use.",
journal = "Journal of Medical Entomology",
title = "Chemosensory Responses to the Repellent Nepeta Essential Oil and Its Major Component Nepetalactone by Aedes aegypti (Diptera: Culicidae), a Vector of Zika Virus",
number = "4",
volume = "54",
doi = "10.1093/jme/tjx059",
pages = "957-963"
}

Sparks, J. T., Bohbot, J. D., Ristić, M., Mišić, D., Skorić, M., Mattoo, A.,& Dickens, J. C.. (2017). Chemosensory Responses to the Repellent Nepeta Essential Oil and Its Major Component Nepetalactone by Aedes aegypti (Diptera: Culicidae), a Vector of Zika Virus. in Journal of Medical Entomology, 54(4), 957-963.
https://doi.org/10.1093/jme/tjx059

Sparks JT, Bohbot JD, Ristić M, Mišić D, Skorić M, Mattoo A, Dickens JC. Chemosensory Responses to the Repellent Nepeta Essential Oil and Its Major Component Nepetalactone by Aedes aegypti (Diptera: Culicidae), a Vector of Zika Virus. in Journal of Medical Entomology. 2017;54(4):957-963.
doi:10.1093/jme/tjx059 .

Sparks, Jackson T., Bohbot, Jonathan D., Ristić, Mihailo, Mišić, Danijela, Skorić, Marijana, Mattoo, Autar, Dickens, Joseph C., "Chemosensory Responses to the Repellent Nepeta Essential Oil and Its Major Component Nepetalactone by Aedes aegypti (Diptera: Culicidae), a Vector of Zika Virus" in Journal of Medical Entomology, 54, no. 4 (2017):957-963,
https://doi.org/10.1093/jme/tjx059 . .