TY  - JOUR
AU  - Rashed, Khaled N.
AU  - Ćirić, Ana
AU  - Glamočlija, Jasmina
AU  - Calhelha, Ricardo C.
AU  - Ferreira, Isabel C.F.R.
AU  - Soković, Marina
PY  - 2018
UR  - http://jjbs.hu.edu.jo/files/v11n3/Paper Number 6.pdf
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/3115
AB  - This study was carried out to evaluate the antibacterial, antifungal and cytotoxic effects of chloroform, ethyl acetate and aqueous fractions obtained from a methanol 80 % extract of Cestrum nocturnum L. (family Solanaceae) aerial parts, and to investigate the bioactive constituents present in these fractions. The results showed that the chloroform fraction had the highest antibacterial effect and cytotoxicity against lung, colon and hepatocellular carcinoma cell lines, while the ethyl acetate fraction displayed the highest antifungal activity and cytotoxicity against cervical carcinoma cell lines. Phytochemical analysis showed the presence of triterpenes, coumarins and flavonoids in the chloroform fraction. Flavonoids, triterpenes and carbohydrates in the ethyl acetate fraction while tannins, flavonoids, saponins, carbohydrates and triterpenes were detected in the aqueous fraction. β-sitosterol, stigmasterol, protocatechuic acid and apigenin were isolated from the chloroform fraction; Kaempferol 8-O-methyl ether, kaempferol, kaempferol 3-O-α-rhamnoside and luteolin 7-O-β-glucoside were isolated from the ethyl acetate fraction, while kaempferol di-sugars: kaempferol 3-O-β-glucoside-7-O-α-rhamnoside and kaempferol 3,7-di-O-α-rhamnoside, were isolated from the aqueous fraction. This study proves the bioactivities of C. nocturnum aerial parts that can be explored as a source of medicinal compounds.
T2  - Jordan Journal of Biological Sciences
T1  - Identification of the bioactive constituents and the antibacterial, antifungal and cytotoxic activities of different fractions from Cestrum nocturnum L.
IS  - 3
VL  - 11
SP  - 273
EP  - 279
UR  - https://hdl.handle.net/21.15107/rcub_ibiss_3115
ER  - 

@article{
author = "Rashed, Khaled N. and Ćirić, Ana and Glamočlija, Jasmina and Calhelha, Ricardo C. and Ferreira, Isabel C.F.R. and Soković, Marina",
year = "2018",
abstract = "This study was carried out to evaluate the antibacterial, antifungal and cytotoxic effects of chloroform, ethyl acetate and aqueous fractions obtained from a methanol 80 % extract of Cestrum nocturnum L. (family Solanaceae) aerial parts, and to investigate the bioactive constituents present in these fractions. The results showed that the chloroform fraction had the highest antibacterial effect and cytotoxicity against lung, colon and hepatocellular carcinoma cell lines, while the ethyl acetate fraction displayed the highest antifungal activity and cytotoxicity against cervical carcinoma cell lines. Phytochemical analysis showed the presence of triterpenes, coumarins and flavonoids in the chloroform fraction. Flavonoids, triterpenes and carbohydrates in the ethyl acetate fraction while tannins, flavonoids, saponins, carbohydrates and triterpenes were detected in the aqueous fraction. β-sitosterol, stigmasterol, protocatechuic acid and apigenin were isolated from the chloroform fraction; Kaempferol 8-O-methyl ether, kaempferol, kaempferol 3-O-α-rhamnoside and luteolin 7-O-β-glucoside were isolated from the ethyl acetate fraction, while kaempferol di-sugars: kaempferol 3-O-β-glucoside-7-O-α-rhamnoside and kaempferol 3,7-di-O-α-rhamnoside, were isolated from the aqueous fraction. This study proves the bioactivities of C. nocturnum aerial parts that can be explored as a source of medicinal compounds.",
journal = "Jordan Journal of Biological Sciences",
title = "Identification of the bioactive constituents and the antibacterial, antifungal and cytotoxic activities of different fractions from Cestrum nocturnum L.",
number = "3",
volume = "11",
pages = "273-279",
url = "https://hdl.handle.net/21.15107/rcub_ibiss_3115"
}

Rashed, K. N., Ćirić, A., Glamočlija, J., Calhelha, R. C., Ferreira, I. C.F.R.,& Soković, M.. (2018). Identification of the bioactive constituents and the antibacterial, antifungal and cytotoxic activities of different fractions from Cestrum nocturnum L.. in Jordan Journal of Biological Sciences, 11(3), 273-279.
https://hdl.handle.net/21.15107/rcub_ibiss_3115

Rashed KN, Ćirić A, Glamočlija J, Calhelha RC, Ferreira IC, Soković M. Identification of the bioactive constituents and the antibacterial, antifungal and cytotoxic activities of different fractions from Cestrum nocturnum L.. in Jordan Journal of Biological Sciences. 2018;11(3):273-279.
https://hdl.handle.net/21.15107/rcub_ibiss_3115 .

Rashed, Khaled N., Ćirić, Ana, Glamočlija, Jasmina, Calhelha, Ricardo C., Ferreira, Isabel C.F.R., Soković, Marina, "Identification of the bioactive constituents and the antibacterial, antifungal and cytotoxic activities of different fractions from Cestrum nocturnum L." in Jordan Journal of Biological Sciences, 11, no. 3 (2018):273-279,
https://hdl.handle.net/21.15107/rcub_ibiss_3115 .