TY  - JOUR
AU  - Senio, Sylwia
AU  - Pereira, Carla
AU  - Vaz, Josiana
AU  - Soković, Marina
AU  - Barros, Lillian
AU  - Ferreira, Isabel C.F.R.
PY  - 2018
UR  - https://www.sciencedirect.com/science/article/pii/S0926669018303650?via%3Dihub
UR  - https://radar.ibiss.bg.ac.rs/handle/123456789/3050
AB  - Galium aparine L. is a very disseminated plant in temperate zones, commonly known as clivers or bedstraw, belonging to the Rubiaceae family and it is traditionally used for its medicinal applications. In this study, G. aparine hydromethanolic extracts and infusions were prepared from air-dried and freeze-dried samples in order to assess their phenolic profile, antioxidant, antimicrobial, and cytotoxic properties. All the studied extracts revealed a similar phenolic profile, but the hydromethanolic extract obtained from the freeze-dried sample presented the highest concentration of phenolic compounds, followed by the respective infusion and the air-dried sample hydromethanolic extract. The major compound detected in the extracts was 5-O-caffeoylquinic acid (from 145 to 163 mg/g extract). Regarding the bioactivity, in general, the extracts presenting higher phenolic concentrations also revealed enhanced bioactive properties. The EC50 values obtained in the antioxidant activity assays ranged from 13.5 to 884 μg/mL, with the freeze-dried sample hydromethanolic extract presenting the highest activity (13.5–555 μg/mL). Similar conclusions could be made in terms of antimicrobial properties, with this extract showing the lowest MIC (1.85–15 mg/mL), MBC (3.75–7.5 mg/mL), and MFC (3.75–20 mg/mL) values. None of the extracts revealed cytotoxicity. The results obtained in this study suggested that G. aparine extracts can be a good source of phenolic compounds with antioxidant and antimicrobial properties.
T2  - Industrial Crops and Products
T1  - Dehydration process influences the phenolic profile, antioxidant and antimicrobial properties of Galium aparine L.
VL  - 120
DO  - 10.1016/J.INDCROP.2018.04.054
SP  - 97
EP  - 103
ER  - 

@article{
author = "Senio, Sylwia and Pereira, Carla and Vaz, Josiana and Soković, Marina and Barros, Lillian and Ferreira, Isabel C.F.R.",
year = "2018",
abstract = "Galium aparine L. is a very disseminated plant in temperate zones, commonly known as clivers or bedstraw, belonging to the Rubiaceae family and it is traditionally used for its medicinal applications. In this study, G. aparine hydromethanolic extracts and infusions were prepared from air-dried and freeze-dried samples in order to assess their phenolic profile, antioxidant, antimicrobial, and cytotoxic properties. All the studied extracts revealed a similar phenolic profile, but the hydromethanolic extract obtained from the freeze-dried sample presented the highest concentration of phenolic compounds, followed by the respective infusion and the air-dried sample hydromethanolic extract. The major compound detected in the extracts was 5-O-caffeoylquinic acid (from 145 to 163 mg/g extract). Regarding the bioactivity, in general, the extracts presenting higher phenolic concentrations also revealed enhanced bioactive properties. The EC50 values obtained in the antioxidant activity assays ranged from 13.5 to 884 μg/mL, with the freeze-dried sample hydromethanolic extract presenting the highest activity (13.5–555 μg/mL). Similar conclusions could be made in terms of antimicrobial properties, with this extract showing the lowest MIC (1.85–15 mg/mL), MBC (3.75–7.5 mg/mL), and MFC (3.75–20 mg/mL) values. None of the extracts revealed cytotoxicity. The results obtained in this study suggested that G. aparine extracts can be a good source of phenolic compounds with antioxidant and antimicrobial properties.",
journal = "Industrial Crops and Products",
title = "Dehydration process influences the phenolic profile, antioxidant and antimicrobial properties of Galium aparine L.",
volume = "120",
doi = "10.1016/J.INDCROP.2018.04.054",
pages = "97-103"
}

Senio, S., Pereira, C., Vaz, J., Soković, M., Barros, L.,& Ferreira, I. C.F.R.. (2018). Dehydration process influences the phenolic profile, antioxidant and antimicrobial properties of Galium aparine L.. in Industrial Crops and Products, 120, 97-103.
https://doi.org/10.1016/J.INDCROP.2018.04.054

Senio S, Pereira C, Vaz J, Soković M, Barros L, Ferreira IC. Dehydration process influences the phenolic profile, antioxidant and antimicrobial properties of Galium aparine L.. in Industrial Crops and Products. 2018;120:97-103.
doi:10.1016/J.INDCROP.2018.04.054 .

Senio, Sylwia, Pereira, Carla, Vaz, Josiana, Soković, Marina, Barros, Lillian, Ferreira, Isabel C.F.R., "Dehydration process influences the phenolic profile, antioxidant and antimicrobial properties of Galium aparine L." in Industrial Crops and Products, 120 (2018):97-103,
https://doi.org/10.1016/J.INDCROP.2018.04.054 . .