Cytotoxic activity of sesquiterpene lactones from Inula britannica on human cancer cell lines

Fischedick, Justin T; Pešić, Milica; Podolski-Renić, Ana; Banković, Jasna Z.; de Vos, Ric CH; Perić, Marija; Todorović, Slađana; Tanić, Nikola T

dc.creator	Fischedick, Justin T
dc.creator	Pešić, Milica
dc.creator	Podolski-Renić, Ana
dc.creator	Banković, Jasna Z.
dc.creator	de Vos, Ric CH
dc.creator	Perić, Marija
dc.creator	Todorović, Slađana
dc.creator	Tanić, Nikola T
dc.date.accessioned	2017-11-23T11:12:00Z
dc.date.available	2015-11-17T10:26:51Z
dc.date.issued	2013	sr
dc.identifier.issn	1874-3900	sr
dc.identifier.other	Rad_konverzija_3011	sr
dc.identifier.uri	https://radar.ibiss.bg.ac.rs/handle/123456789/1016
dc.description.abstract	Five new sesquiterpene lactones (1-5) were isolated from Inula britannica collected in the wild from Serbia along with five known compounds (6-10). Sesquiterpene lactones were isolated using centrifugal partition chromatography followed by combination of flash chromatography and semi-preparative HPLC. Isolated compounds were screened for cytotoxic activity on four different human cancer cell lines and their multi-drug resistant counterparts, as well as on normal human keratinocytes. Sesquiterpene lactones showed similar cytotoxic activity toward drug sensitive and drug resistant cancer cell lines. (C) 2013 Phytochemical Society of Europe. Published by Elsevier B. V. All rights reserved.	en
dc.description.sponsorship	European Union [227448]; Center for Biosystems Genomics part of the Netherlands Genomics Initiative; Netherlands Metabolomics Center part of the Netherlands Genomics Initiative	en
dc.language.iso	English	sr
dc.rights	restrictedAccess
dc.source	Phytochemistry Letters	sr
dc.title	Cytotoxic activity of sesquiterpene lactones from Inula britannica on human cancer cell lines	en
dc.type	article
dc.rights.license	ARR
dcterms.abstract	Песић, Милица М; Фисцхедицк, Јустин Т; Подолски-Ренић, Aна М.; Банковић, Јасна З.; де Вос, Риц ЦХ; Перић, Марија; Тодоровић, Слађана И; Танић, Никола Т;
dc.citation.issue	2	sr
dc.citation.volume	6	sr
dc.citation.spage	1	sr
dc.citation.epage	252	sr
dc.type.version	publishedVersion	en
dc.citation.rank	M22
dc.identifier.rcub	https://hdl.handle.net/21.15107/rcub_ibiss_1016

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