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Antioxidative defense organization in retroperitoneal white adipose tissue during acclimation to cold-The involvement of L-arginine/NO pathway
dc.creator | Janković, Aleksandra | |
dc.creator | Buzadžić, Biljana J. | |
dc.creator | Korac, Aleksandra B | |
dc.creator | Otašević, Vesna | |
dc.creator | Vasilijević, Ana | |
dc.creator | Korać, Bato | |
dc.date.accessioned | 2017-11-23T11:12:14Z | |
dc.date.available | 2900-01-01 | |
dc.date.issued | 2009 | sr |
dc.identifier.issn | 0306-4565 | sr |
dc.identifier.other | Rad_konverzija_3125 | sr |
dc.identifier.uri | https://radar.ibiss.bg.ac.rs/handle/123456789/1130 | |
dc.description.abstract | 1. Retroperitoneal white adipose tissue (RpWAT) antioxidative defense was investigated in untreated, L-arginine-treated and N(omega)-nitro-L-arginine methyl ester (L-NAME)-treated rats kept at 4 +/- 1 degrees C (1, 3, 7, 12, 21 and 45 days) and compared to control rats at 22 +/- 1 degrees C. 2. Cold-acclimation-induced RpWAT weight decrease was accompanied by a decline in glutathione level and increased activity of manganese superoxide dismutaise (MnSOD), glutathione S-transferase (GST), catalase, glutathione peroxidase and glutathione reductase at different time-points. 3. L-arginine accelerated RpWAT weight decrease, the increase in MnSOD and GST activities and the prolonged increase of catalase, MnSOD and GST activities. L-NAME delayed cold-induced catalase activity increase and tissue weight decrease. Prolonged L-NAME-treatment had a similar effect on RpWAT as L-arginine. 4. Results suggest the involvement Of L-arginine/NO pathway in RpWAT oxidative metabolic augmentation induced by cold-acclimation. (C) 2009 Elsevier Ltd. All rights reserved. | en |
dc.description.sponsorship | Ministry of Science and Technological Development, Republic of Serbia [143050] | sr |
dc.language.iso | English | sr |
dc.publisher | Elsevier | |
dc.rights | restrictedAccess | |
dc.source | Journal of Thermal Biology | sr |
dc.title | Antioxidative defense organization in retroperitoneal white adipose tissue during acclimation to cold-The involvement of L-arginine/NO pathway | en |
dc.type | article | |
dc.rights.license | ARR | |
dcterms.abstract | Василијевић, Aна; Јанковић, Aлександра; Бузаджић, Биљана Ј.; Корац, Aлександра Б; Петровић, Весна; Кораћ, Бато М.; | |
dc.rights.holder | © 2009 Elsevier Ltd. | |
dc.citation.issue | 7 | sr |
dc.citation.volume | 34 | sr |
dc.identifier.doi | 10.1016/j.jtherbio.2009.06.007 | |
dc.identifier.scopus | 2-s2.0-70349974703 | |
dc.identifier.wos | 000271441200007 | |
dc.citation.spage | 358 | sr |
dc.citation.epage | 365 | sr |
dc.type.version | publishedVersion | en |
dc.citation.rank | M22 | |
dc.identifier.rcub | https://hdl.handle.net/21.15107/rcub_ibiss_1130 |