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Dietary restriction modulates alpha-synuclein expression in the aging rat cortex and hippocampus
dc.creator | Mladenović, Aleksandra | |
dc.creator | Perović, Milka | |
dc.creator | Tanić, Nikola T | |
dc.creator | Petanceska, Suzana | |
dc.creator | Ruždijić, Sabera | |
dc.creator | Kanazir, Selma | |
dc.date.accessioned | 2017-11-23T11:15:08Z | |
dc.date.available | 2015-11-17T10:26:51Z | |
dc.date.issued | 2007 | sr |
dc.identifier.issn | 0887-4476 | sr |
dc.identifier.other | Rad_konverzija_3579 | sr |
dc.identifier.uri | https://radar.ibiss.bg.ac.rs/handle/123456789/1584 | |
dc.description.abstract | Dietary restriction (DR) is one of the promising environmental interventions known to attenuate aging and decrease risk of age-related neurodegenerative disorders. The aim of this study was to assess the effects of DR on expression of a-synuclein, a presynaptic protein involved in pathogenesis of Parkinson's and some other neurodegenerative diseases, in the cortex and hippocampus of adult, middle-aged, late middle-aged, and aged rats. Using Real Time RT-PCR, the authors report that aging regulates the expression of alpha-synuclein in a tissue-specific manner and that long-term DR reverts the late age-related changes of alpha-synuclein expression. (c) 2007 Wiley-Liss, Inc. | en |
dc.description.sponsorship | null | sr |
dc.language.iso | English | sr |
dc.rights | restrictedAccess | |
dc.source | Synapse | sr |
dc.title | Dietary restriction modulates alpha-synuclein expression in the aging rat cortex and hippocampus | en |
dc.type | article | |
dc.rights.license | ARR | |
dcterms.abstract | Танић, Никола Т; Каназир, Селма Д.; Младеновић Ђорђевић, Aлександра; Руждијић, Сабера; Петанцеска, Сузана; Перовић, Милка; | |
dc.citation.issue | 9 | sr |
dc.citation.volume | 61 | sr |
dc.citation.epage | 794 | sr |
dc.type.version | publishedVersion | en |
dc.citation.rank | M22 | |
dc.identifier.rcub | https://hdl.handle.net/21.15107/rcub_ibiss_1584 |
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