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Different effects of adenosine A1 agonist ribavirin on amphetamine-induced total locomotor and stereotypic activities in rats
dc.creator | Petković, Branka | |
dc.creator | Pešić, Vesna | |
dc.creator | Peković, Sanja | |
dc.creator | Rakić, Ljubiša | |
dc.creator | Stojiljković, Mirjana B | |
dc.date.accessioned | 2017-11-23T11:15:05Z | |
dc.date.available | 2900-01-01 | |
dc.date.issued | 2005 | sr |
dc.identifier.issn | 0077-8923 | sr |
dc.identifier.other | Rad_konverzija_3634 | sr |
dc.identifier.uri | https://radar.ibiss.bg.ac.rs/handle/123456789/1639 | |
dc.identifier.uri | https://nyaspubs.onlinelibrary.wiley.com/doi/abs/10.1196/annals.1342.048 | |
dc.description.abstract | Pretreatment with a single dose of ribavirin (10, 20, and 30 mg/kg b.w., i.p.) decreased amphetamine (1.5 mg/kg b.w., i.p.)-induced total locomotor activity (distance traveled) compared to amphetamine alone, but the most significant effect was observed with 30 mg/kg dose. In contrast, total stereotypic activities (such as sniffing, self-grooming, licking, and head weaving) of these animals were unchanged. These findings demonstrate the ability of ribavirin to modulate in a different way central regulation of locomotor and stereotypic activities that in the future could have a practical application in target therapy of some movement disorders. | en |
dc.description.sponsorship | null | sr |
dc.language.iso | English | sr |
dc.publisher | New York Academy of Sciences | |
dc.relation | Ministry of Science and Environmental Protection of the Republic of Serbia (Contract #1647) | |
dc.rights | restrictedAccess | |
dc.source | Annals of the New York Academy of Sciences: Biophysics from Molecules to Brain: in Memory of Radoslav K. Andjus | sr |
dc.subject | Ribavirin | |
dc.subject | Amphetamine | |
dc.subject | Locomotion | |
dc.subject | Stereotypy | |
dc.subject | Rats | |
dc.title | Different effects of adenosine A1 agonist ribavirin on amphetamine-induced total locomotor and stereotypic activities in rats | en |
dc.type | conferenceObject | |
dc.rights.license | ARR | |
dcterms.abstract | Стојиљковић, Мирјана Б; Пековић, Сања М.; Јанац, Бранка Б.; Ракић, Љубиса; Песић, Весна Т; | |
dc.rights.holder | © 2005 New York Academy of Sciences | |
dc.citation.volume | 1048 | sr |
dc.description.other | Biophysics from Molecules to Brain: in Memory of Radoslav K. Andjus. New York, USA: Academy of Sciences; 2005. p. 396-9. (Annals of the New York Academy of Sciences; Vol. 1048). | en |
dc.identifier.doi | 10.1196/annals.1342.048 | |
dc.identifier.pmid | 16154961 | |
dc.identifier.scopus | 2-s2.0-25144473004 | |
dc.identifier.wos | 000233712300045 | |
dc.citation.spage | 396 | |
dc.citation.epage | 399 | sr |
dc.type.version | publishedVersion | en |
dc.citation.rank | M21 |