Chemical composition and antifungal activities of essential oils from leaves, calyx and corolla of Salvia brachyodon Vandas

Abstract

The chemical composition and antifungal activity of the corolla, calyx and leaf oils of Salvia brachyodon were analyzed by GC and GUMS. The oils were hydrodistilled from the leaves, corolla and calyx, separately. The leaf oil contained 1,8-cineole (33.0%), alpha-pinene (12.7%), camphene (12.5%) and beta-pinene (11.3%) as the most abundant constituents. The oil isolated from the calyx contained beta-pinene (27.6%), alpha-pinene (16.2%), camphene (13.7%), borneol (13.2%) and camphor (12.4%) as major components, while in the corolla oil the main components were beta-pinene (31.7%), borneol (12.8%), alpha-pinene (11.8%), camphene (6.7%) and alpha-pinene (11.8%). The last sample, however, was the most complex, because of the presence of higher concentration of sesquiterpenes and presence of diterpenes, which were not recorded in the other samples investigated. Antifungal activities of the essential oils were determined by the microdilution method against Aspergillus niger, Trichophyton mentagrophytes and Candida albicans. The oil from the calyx possessed the best antifungal activity against all the fungal species tested.