Sex-specific effects of sympatric mitonuclear variation on fitness in Drosophila subobscura
2015
Аутори:
Jelic, MihailoArnqvist, Goran
Kurbalija Novičić, Zorana
Kenig, Bojan
Tanaskovic, Marija
Anđelković, Marko
Stamenković-Radak, Marina
Тип документа:
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт:
Background: A number of recent studies have shown that the pattern of
mitochondrial DNA variation and evolution is at odds with a neutral
equilibrium model. Theory has suggested that selection on mitonuclear
genotypes can act to maintain stable mitonuclear polymorphism within
populations. However, this effect largely relies upon selection being
either sex-specific or frequency dependent. Here, we use mitonuclear
introgression lines to assess differences in a series of key
life-history traits (egg-to-adult developmental time, viability,
offspring sex-ratio, adult longevity and resistance to desiccation) in
Drosophila subobscura fruit flies carrying one of three different
sympatric mtDNA haplotypes.
Results: We found functional differences between these sympatric mtDNA
haplotypes, but these effects were contingent upon the nuclear genome
with which they were co-expressed. Further, we demonstrate a significant
mitonuclear genetic effect on adult sex ratio, as well as a sex x mtDNA
x nuDNA interaction for adult longevity.
Conclusions: The observed effects suggest that sex specific mitonuclear
selection contributes to the maintenance of mtDNA polymorphism and to
mitonuclear linkage disequilibrium in this model system.
Кључне речи:
Mitochondria; Mitonuclear epistasis; Life history traits; Sexual dimorphism; Selection; Fruit flyИзвор:
Bmc Evolutionary Biology, 2015, 15
DOI: 10.1186/s12862-015-0421-2
ISSN: 1471-2148