Histological Effects of Enamel Matrix Derivative on Exposed Dental Pulp
2015
Аутори:
Popovic Bajic, MarijanaDanilovic, Vesna
Prokic, Branislav
Prokic, Bogomir Bolka
Manojlovic, Milica
Zivkovic, Slavoljub
Тип документа:
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт:
Introduction Direct pulp capping procedure is a therapeutic application
of a drug on exposed tooth pulp in order to ensure the closure of the
pulp chamber and to allow the healing process to take place.
Objective The aim of this study was to examine the histological effects
of Emdogain (R) on exposed tooth pulp of a Vietnamese pig (Sus scrofa
verus).
Methods The study comprised 20 teeth of a Vietnamese pig. After class V
preparation on the buccal surfaces of incisors, canines and first
premolars, pulp was exposed. In the experimental group, the perforations
were capped with Emdogain (R) (Straumann, Basel, Switzerland), while in
the control group pulp capping was performed with MTA (R) (Dentsply
Tulsa Dental, Johnson City, TN, USA). All cavities were restored with
glass-ionomer cement (GC Fuji VIII, GC Corporation,Tokyo,Japan).The
observational period was 28 days, after which the animal was sacrificed
and histological preparations were made. A light microscope was used to
analyze dentin bridge formation, tissue reorganization and inflammation,
and the presence of bacteria in the pulp.
Results The formation of dentin bridge was observed in the experimental
and control groups. Inflammation of the pulp was mild to moderate in
both groups. Angiogenesis and many odontoblast-like cells, responsible
for dentin bridge formation, were observed. Necrosis was not observed in
any case, nor were bacteria present in the pulp.
Conclusion Histological analysis indicated a favorable therapeutic
effect of Emdogain (R) Gel in direct pulp capping of Vietnamese pigs.
Pulp reaction was similar to that of MTA (R).
Кључне речи:
direct pulp capping; enamel protein; Vietnamese pigИзвор:
Srpski Arhiv Za Celokupno Lekarstvo, 2015, 143, 7-8, 397-403
DOI: 10.2298/SARH1508397P
ISSN: 0370-8179