Chemical features of Ganoderma polysaccharides with antioxidant, antitumor and antimicrobial activities
2015
Аутори:
Ferreira, Isabel C. F. R.Heleno, Sandrina A.
Reis, Filipa S.
Stojković, Dejan
Queiroz, Maria Joao R. P.
Helena Vasconcelos, M.
Soković, Marina
Тип документа:
Приказ (Објављена верзија)
,
© 2014 Elsevier Ltd
Метаподаци
Приказ свих података о документуАпстракт:
Ganoderma genus comprises one of the most commonly studied species
worldwide, Ganoderma lucidum. However, other Ganoderma species have been
also reported as important sources of bioactive compounds.
Polysaccharides are important contributors to the medicinal properties
reported for Ganoderma species, as demonstrated by the numerous
publications, including reviews, on this matter. Yet, what are the
chemical features of Ganoderma polysaccharides that have bioactivity? In
the present manuscript, the chemical features of Ganoderma
polysaccharides with reported antioxidant, antitumor and antimicrobial
activities (the most studied worldwide) are analyzed in detail. The
composition of sugars (homo- versus hetero-glucans and other
polysaccharides), type of glycosidic linkages, branching patterns, and
linkage to proteins are discussed. Methods for extraction, isolation and
identification are evaluated and, finally, the bioactivity of
polysaccharidic extracts and purified compounds are discussed. The
integration of data allows deduction of structure-activity relationships
and gives clues to the chemical aspects involved in Ganoderma
bioactivity. (C) 2014 Elsevier Ltd. All rights reserved.
Кључне речи:
Ganoderma; Polysaccharides; Chemical features; Bioactivity; Structure-activityИзвор:
Phytochemistry, 2015, 114, SI, 38-55
DOI: 10.1016/j.phytochem.2014.10.011
ISSN: 0031-9422
PubMed: 25457487