Biomarkers of Oxidative Stress and Acetylcholinesterase Activity in the Blood of Grass Snake (Natrix natrix L.) during Prehibernation and Posthibernation Periods
2015
Аутори:
Gavrić, JelenaProkic, Marko
Despotovic, Svetlana
Gavrilović, Branka
Radovanović, Tijana
Borković Mitić, Slavica
Pavlović, Slađan
Saičić, Zorica
Тип документа:
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт:
This work examined the enzymatic (superoxide dismutase-CuZn SOD,
catalase-CAT, glutathione peroxidase-GSH-Px, glutathione reductase-GR,
and the biotransformation phase II enzyme glutathione-S-transferase-GST)
and nonenzymatic (total glutathione-GSH and lipid peroxides-TBARS
concentrations) biomarkers of oxidative stress and acetylcholinesterase
(AChE) activity in the blood of the grass snake (Natrix natrix L.)
during prehibernation and posthibernation. The animals were collected in
October (prehibernation) and April (posthibernation) at the nature
reserve Obedska Bara (OB) and industrial region Pancevacki Rit (PR) in
Serbia. In posthibernation, decreased CAT activity and TBARS
concentration in specimens from PR, and decreased GR and AChE
activities, and TBARS concentration in specimens from OB were observed,
whereas GR and GST activities and GSH concentration were significantly
elevated in the specimens from PR. In prehibernation, CAT activity and
GSH concentration were increased, while GSH-Px, GR, GST and AChE
activities and TBARS concentration were decreased in the specimens from
PR when compared to animals from OB. During the posthibernation, the
activity of CuZn SOD was decreased, while GST and AChE activities were
increased in the specimens from PR when compared to the specimens from
OB. These differences represented an adaptive mechanism to oxidative
stress induced by tissue reoxygenation during arousal from hibernation
and could be modulated by environmental pollution.
Кључне речи:
Grass snake; oxidative stress; hibernation; Acetylcholinesterase; antioxidant enzymesИзвор:
Brazilian Archives of Biology and Technology, 2015, 58, 3, 443-453
DOI: 10.1590/S1516-8913201500308
ISSN: 1678-4324