Rosa canina L. - new possibilities for an old medicinal herb
2015
Аутори:
Živković, JelenaStojković, Dejan
Petrović, Jovana
Zdunić, Gordana
Glamočlija, Jasmina
Soković, Marina
Тип документа:
Чланак у часопису (Објављена верзија)
,
© 2015 The Royal Society of Chemistry
Метаподаци
Приказ свих података о документуАпстракт:
Health beneficial properties of Rosa canina species are mainly
attributed to rose hips, while the leaves are usually discarded as
waste. In the present study we investigated chemical constituents as
well as antimicrobial and antibiofilm potential of R. canina methanolic
leaf extract. Chemical analysis showed that dominant phenolic compounds
are quercetin and isorhamnetin derivatives (isoquercetin and
isorhamnetin-3-O-rutinoside). Among the tested bacteria, Pseudomonas
aeruginosa and Salmonella typhimurium were the most susceptible to the
activity of R. canina leaf extract with MIC and MBC values both 0.009 mg
mL(-1). For most of the bacterial strains investigated the extract
showed significantly higher activity compared to the used standard
compounds streptomycin and ampicillin. Also the tested extract
powerfully inhibited in vitro biofilm growth in Pseudomonas aeruginosa,
Staphylococcus aureus, Leishmania monocytogenes and Escherichia coli at
sub MIC-levels. With concentrations equal to 1/4 and 1/8 of MIC values
biofilm growth of P. aeruginosa and E. coli was inhibited by 90\%. The
obtained results are significant for a wider and efficient use of R.
canina leaves.
Напомена:
This article has been corrected http://dx.doi.org/10.1039/c5fo90042e.
Извор:
Food & Function, 2015, 6, 12, 3687-3692Финансирање / пројекти:
- Карактеризација и примена метаболита гљива и утврђивање потенцијала нових биофунгицида (RS-173032)
- Магматски, метаморфни и седиментни процеси алпског орогена у централном делу Балканског полуострва (RS-146013)
DOI: 10.1039/c5fo00820d
ISSN: 2042-650X