Quercetin Potently Reduces Biofilm Formation of the Strain Pseudomonas aeruginosa PAO1 in vitro
2015
Аутори:
Pejin, BorisĆirić, Ana
Markovic, Jasmina D.
Glamočlija, Jasmina
Nikolić, Miloš
Stanimirovic, Bojana
Soković, Marina
Тип документа:
Чланак у часопису (Објављена верзија)
Метаподаци
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This work was focused on in vitro evaluation of anti-biofilm and
anti-quorum sensing effects of four selected flavonoid compounds
/(+)-catechin, caffeic acid, quercetin and morin/using the strain
Pseudomonas aeruginosa PAO1. At a concentration of 0.5 MIC quercetin was
the only compound found to potently reduce both P. aeruginosa biofilm
formation (95\%) and its twitching motility. The chemical scaffold of
quercetin, a common dietary polyphenol, may actually inspire development
of novel and more effective medicinal agents targeting P. aeruginosa,
the bacterium well known for its resistance.