Genetic detection of Dobrava-Belgrade hantavirus in the edible dormouse (Glis glis) in central Serbia
2015
Аутори:
Stanojevic, M.Nikolic, V.
Stajkovic, N.
Stamenković, Gorana
Bozovic, B.
Cekanac, R.
Marusic, P.
Gligic, A.
Тип документа:
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт:
Hantaviruses are endemic in the Balkans, particularly in Serbia, where
sporadic cases and/or outbreaks of hantaviral human disease have been
reported repeatedly, and evidenced serologically. Here, we present
genetic detection of Dobrava-Belgrade virus (DOBV) hantaviral sequences
in wild rodents trapped in central Serbia. All the animals were
pre-screened serologically by indirect immunofluorescence (IF) test and
only those with a positive finding of hantaviral antigens were further
tested by polymerase chain reaction. Of the total of 104 trapped
animals, 20 were found to be IF positive and of those three were
positive for hantaviral RNA: one Microtus arvalis for Tula virus, and
one each of Apodemus agrarius and Glis glis for DOBV. Phylogenetic
analysis of the obtained sequences implies putative DOBV spillover
infection of A. agrarius and G. glis from Apodemus flavicollis. However,
future investigations should help to identify the most common natural
host and geographical distribution of DOBV in its reservoir hosts in
Serbia.
Кључне речи:
Balkans; Glis glisИзвор:
Epidemiology and Infection, 2015, 143, 2, 400-404
DOI: 10.1017/S0950268814001010
ISSN: 1469-4409