Chemical characterization of the medicinal mushroom Phellinus linteus (Berkeley & Curtis) Teng and contribution of different fractions to its bioactivity
2014
Authors:
Reis, Filipa S.Barreira, Joao C. M.
Calhelha, Ricardo C.
van Griensven, Leo J. I. D.
Ćirić, Ana
Glamočlija, Jasmina
Soković, Marina
Ferreira, Isabel C. F. R.
Document Type:
Article (Published version)
,
© 2014 Elsevier Ltd.
Metadata
Show full item recordAbstract:
Mushrooms are widely appreciated for their organoleptic qualities, being
also recognized as good sources of bioactive compounds that provide
antioxidant, antimicrobial and cytotoxic activities. Polysaccharides
(including glucans) are often pointed out as the most bioactive
compounds isolated from mushrooms, but other molecules such as
triterpenoids, might also be highlighted for their bioactivity. In
scientific research, when isolated compounds are used, potential
synergistic effects might be lost. Accordingly, the bioactivity of
Phellinus linteus was evaluated in selected fractions (polysaccharides,
glucans and triterpenoids), as well as in the methanolic and ethanolic
extracts. The best antioxidant and antibacterial activities were
obtained with methanolic extract, while glucan and triterpenoid
fractions gave the strongest antifungal activity. In contrast, ethanolic
extract gave the best results in cytotoxic activity, indicating that the
bioactive compounds present might act synergistically. The
differentiated activity of P. linteus fractions and extracts could be
useful to find antimicrobial, antioxidant and cytotoxic agents as
alternatives to synthetic chemicals with application in agriculture,
food industry or pharmacy. (C) 2014 Elsevier Ltd. All rights reserved.
Keywords:
Phellinus linteus; Bioactive compounds; Antioxidant; Antimicrobial; CytotoxicSource:
Lwt-Food Science and Technology, 2014, 58, 2, 478-485Funding / projects:
- Characterization and application of fungal metabolites and assessment of new biofungicides potential (RS-MESTD-Basic Research (BR or ON)-173032)
DOI: 10.1016/j.lwt.2014.04.013
ISSN: 0023-6438