Antibacterial and antifungal activities of methanol extract and phenolic compounds from Diospyros virginiana L.
2014
Tip dokumenta:
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt:
This study was carried out with the objective to investigate
antibacterial and antifungal activities of Diospyros virginiana fruits
(methanol 80\%) extract and the phenolic compounds isolated from the
extract. The in vitro antibacterial and antifungal assays were done
against eight bacterial strains and against eight fungal species using
microdilution method. Eight phenolic compounds, m-gallate, gallic acid,
luteolin, quercetin, myricetin, myricetin 3-O-alpha-rhamnoside,
myricetin 3-O-beta-glucoside, and myricetin 3-O-beta-glucuronide were
isolated and identified by different spectroscopic tools (UV, H-1 NMR,
C-13 NMR, MS). The results of the methanol extract of Diospyros
virginiana fruits and its isolated phenolic compounds showed significant
antibacterial and antifungal effects against all the tested
microorganisms. The best results were obtained for flavonoid aglycones
which showed strong antimicrobial activity against all the
microorganisms tested. These results may help to discover new chemical
classes of natural antimicrobial substances that could serve as
selective agents for infectious disease chemotherapy and control. (C)
2014 Published by Elsevier B.V.
Ključne reči:
Diospyros virginiana; Fruits; Phenolic compounds; Antibacterial; AntifungalIzvor:
Industrial Crops and Products, 2014, 59, 210-215
DOI: 10.1016/j.indcrop.2014.05.021
ISSN: 1872-633X