Приказ основних података о документу

dc.creatorPejin, Boris
dc.creatorTalevski, Aleksandra
dc.creatorĆirić, Ana
dc.creatorGlamočlija, Jasmina
dc.creatorNikolić, Miloš
dc.creatorTalevski, Trajce
dc.creatorSoković, Marina
dc.date.accessioned2016-05-23T11:00:45Z
dc.date.available2016-05-23T11:00:45Z
dc.date.issued2014
dc.identifier.issn1478-6427
dc.identifier.urihttps://radar.ibiss.bg.ac.rs/handle/123456789/2280
dc.description.abstractThe antimicrobial activity of five crude extracts (aqueous, methanol, ethyl acetate, acetone and methylene chloride) of the freshwater sponge Ochridaspongia rotunda (Arndt, 1937) was evaluated in vitro by using microdilution method against eight bacterial and eight fungal strains for the first time. The extracts were proven to be active in varying degrees against all the bacteria and fungi tested. O. rotunda methanol extract exhibited the highest antibacterial activity (minimum inhibitory concentration (MIC) 7.5-15.0 mu g/mL and minimum bactericidal concentration 15-30 mu g/mL), while its acetone extract exhibited the most promising antifungal activity (MIC 7.5-45.0 mu g/mL and minimum fungicidal concentration 15-60 mu g/mL). The extracts were more effective against the bacteria and fungi screened compared with the positive controls (streptomycin and ampicillin for bacteria and bifonazole and ketoconazole for fungi, respectively). According to the experimental data obtained, this deepwater sponge species may be considered as a gold mine of new antimicrobial substances with significant and broad-range activity.en
dc.description.sponsorshipMinistry of Education, Science and Technological Development of the Republic of Serbia {[}172053, 173032]
dc.languageEnglish
dc.rightsrestrictedAccess
dc.sourceNatural Product Research
dc.subjectPorifera
dc.subjectendemic species
dc.subjectOhrid
dc.subjectextracts
dc.subjectbacteria
dc.subjectfungi
dc.titleIn vitro evaluation of antimicrobial activity of the freshwater sponge Ochridaspongia rotunda (Arndt, 1937)en
dc.typearticle
dc.rights.licenseARR
dcterms.abstractСоковић, Марина Д.; Талевски, Трајце; Николиц, Милос; Ћирић, Aна Д.; Талевски, Aлександра; Пејин, Борис; Гламочлија, Јасмина;
dc.citation.issue18
dc.citation.volume28
dc.identifier.doi10.1080/14786419.2014.911297
dc.identifier.scopus2-s2.0-84905387420
dc.identifier.wos000340273000012
dc.citation.spage1489
dc.citation.epage1494
dc.type.versionpublishedVersionen


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