Ouabain modulation of snail Br neuron bursting activity after the exposure to 10 mT static magnetic field revealed by Higuchi fractal dimension
2014
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Aim of this study was to investigate the application of normalized mean
of the empirical Higuchi fractal dimension (FD) distributions, as a new
approach to analyze the spontaneous bioelectrical activity of garden
snail (Helix pomatia) Br neuron. The effect of ouabain on modulation of
Br neuron bursting activity before and after the exposure to 10 mT
static magnetic field (SMF) was observed by analyzing the following
parameters: action potential (AP), interspike interval (ISI) and
interbursting interval (IBI) components. Normalized mean of the
empirical FD distributions were formed for the following experimental
conditions: Control 1, Ouabain 1, Control 2, SMF 2, ASMF 2, Control 3,
SMF 3 and Ouabain ASMF 3. Our main results have shown that ouabain
without SMF induced increase in participation of AP and a decrease in
participation of IBI components compared to the first control condition.
However, in the presence of 10 mT SMF, ouabain-induced changes of
measured parameters of Br neuron activity were less pronounced compared
to the third control condition. We have shown that normalized mean of
the empirical FD distributions is a useful method for detecting the
changes in AP, ISI, and IBI components of complex bursting activity in
altered physiological states.
Ključne reči:
Higuchi fractal dimension; Bursting activity; Ouabain; Na+/K+ pump; Static magnetic fieldIzvor:
General Physiology and Biophysics, 2014, 33, 3, 335-344Finansiranje / projekti:
- Ribe kao bioindikatori stanja kvaliteta otvorenih voda Srbije (RS-MESTD-Basic Research (BR or ON)-173045)
- Uticaj magnetnih polja i drugih sredinskih stresora na fiziološke odgovore i ponašanje različitih vrsta (RS-MESTD-Basic Research (BR or ON)-173027)
DOI: 10.4149/gpb_2014010
ISSN: 0231-5882
PubMed: 24968407