RADICAL SCAVENGING AND ANTIMICROBIAL ACTIVITY OF ESSENTIAL OIL AND EXTRACTS OF ECHINOPHORA SIBTHORPIANA GUSS. FROM MACEDONIA
2014
Аутори:
Mileski, KsenijaDžamić, Ana M.
Ćirić, Ana
Grujić, Slavica
Ristić, M.
Matevski, V.
Marin, Petar D.
Тип документа:
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт:
This study was undertaken to determine the antioxidant and antimicrobial
effect of essential oil and extracts of Echinophora sibthorpiana Guss.
(fam. Apiaceae) collected in Macedonia. The chemical composition of E.
sibthorpiana essential oil was characterized by the presence of methyl
eugenol (60.40\%), p-cymene (11.18\%) and a-phellandrene (10.23\%). The
free radical scavenging activity of extracts and essential oil was
evaluated by DPPH and ABTS assays. The aqueous extract of aerial parts
exhibited the strongest scavenging activity (IC50=1.67 mg/ml); results
of the ABTS test showed that the most effective was the ethanol extract
of aerial parts (1.11 mg vit. C/g). The essential oil showed stronger
antioxidant activity compared to hydroxyanisole, ascorbic acid and
quercetin that were used in the DPPH and ABTS tests, respectively. The
total phenolic and flavonoid concentrations in the extracts ranged
between 38.65-60.72 mg GA/g, and 3.15-19.00 mg Qu/g, respectively. The
antimicrobial properties of the extracts and essential oil were
investigated using a micro-well dilution technique against human
pathogenic strains. The results were comparable with the effects of the
positive controls, streptomycin and fluconazole. These findings indicate
that E. sibthorpiana extracts and oil can be used in preventive
treatments and as an alternative for synthetic preservatives.
Кључне речи:
Echinophora sibthorpiana; Apiaceae; essential oil; extracts; phenols; flavonoids; antimicrobial activityИзвор:
Archives of Biological Sciences, 2014, 66, 1, 401-413Финансирање / пројекти:
- Микроморфолошка, фитохемијска и молекуларна истраживања биљака - систематски, еколошки и применљиви аспекти (RS-173029)
- Испитивање лековитог потенцијала биљака: морфолошка, хемијска и фармаколошка карактеризација (RS-173021)
DOI: 10.2298/ABS1401401M
ISSN: 1821-4339