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The effect of SRIH-14 or octreotide on the morphological characteristics of adrenal medulla using newcast
dc.creator | Trifunović, Svetlana | |
dc.creator | Filipović, B. | |
dc.creator | Ajdžanović, Vladimir | |
dc.creator | Manojlović-Stojanoski, Milica | |
dc.creator | Nestorović, Nataša | |
dc.creator | Sekulić, Milka | |
dc.creator | Milošević, Verica | |
dc.date.accessioned | 2015-08-28T10:26:51Z | |
dc.date.available | 2015-08-28T10:26:51Z | |
dc.date.issued | 2010 | sr |
dc.date.issued | 2010 | |
dc.identifier.issn | 0354-4664 | sr |
dc.identifier.other | Rad_konverzija_312 | sr |
dc.identifier.uri | https://radar.ibiss.bg.ac.rs/handle/123456789/248 | |
dc.description.abstract | The effects of chronic treatments with either SRIH-14 or octreotide on the adrenal medulla of male Wistar rats were examined. Adult males received subcutaneous (s.c.) injections of 20 μg/100 g body weight of either SRIH-14 or octreotide twice a day for 28 consecutive days. The absolute weights and the absolute volumes of the adrenal glands significantly (p<0.05) decreased after either treatment. The adrenal medulla was analyzed by histological and stereological methods using newCAST. Compared to the control, the relative volumes of the vascular tissues significantly (p < 0.05) decreased - by 40% and 25% in the SRIH-14- and octreotide-treated groups, respectively. In the SRIH-14- and octreotide-treated groups the relative volumes of chromaffin and interstitial tissue increased by 6% and 5% (p < 0.05), respectively. These findings show that both SRIH-14 and octreotide affect the morphological characteristics of the adrenal zona medullaris in a similar manner. | en |
dc.description.sponsorship | Projekat ministarstva br. 143007B | sr |
dc.language.iso | eng | sr |
dc.rights | openAccess | sr |
dc.source | Archives of Biological Sciences | sr |
dc.subject | SRIH-14 | ENG |
dc.subject | octreotid | ENG |
dc.subject | Adrenal medulla | ENG |
dc.subject | stereology | ENG |
dc.subject | newCAST | ENG |
dc.title | The effect of SRIH-14 or octreotide on the morphological characteristics of adrenal medulla using newcast | en |
dc.type | article | sr |
dc.rights.license | ARR | |
dcterms.abstract | Филиповић, Б.; Aјджановић, Владимир; Трифуновић, Светлана; Секулић, Милка; Манојловић-Стојаноски, Милица; Несторовић, Наташа; Милошевић, Верица; | |
dc.citation.issue | 1 | sr |
dc.citation.volume | 62 | sr |
dc.citation.spage | 93 | sr |
dc.citation.epage | 96 | sr |
dc.type.version | publishedVersion | sr |
dc.identifier.fulltext | https://radar.ibiss.bg.ac.rs//bitstream/id/2029/Rad_konverzija_312.pdf | |
dc.citation.rank | M23 | |
dc.identifier.rcub | https://hdl.handle.net/21.15107/rcub_ibiss_248 |