Protective effects of quercetin and vitamin C against nicotine-induced toxicity in the blood of Wistar rats
Abstract:
Nicotine is a potential inducer of oxidative stress, through which it can damage numerous biological molecules. The aim of our study was to investigate the prooxidative effects of nicotine and protective (additive or synergistic) effects of quercetin and vitamin C in the blood of experimental animals, to determine whether the combination of these antioxidants might be beneficial for clinical purposes. Wistar albino rats were receiving intraperitoneal nicotine injection (0.75 mg kg
Keywords:
Antioxidant defence; Erythrocytes; Lipid profile; Oxidative damage; Reactive oxygen species; TobaccoSource:
Archives of Industrial Hygiene and Toxicology, 2016, 67, 4, 304-310Funding / projects:
- Molecular and physiological biomonitoring of aerobic organisms based on the determination of biochemical biomarkers of oxidative stress (RS-MESTD-Basic Research (BR or ON)-173041)
DOI: 10.1515/aiht-2016-67-2795
ISSN: 0004-1254
PubMed: 28033106
WoS: 000393020600007
Scopus: 2-s2.0-85008698288
URI
http://www.degruyter.com/view/j/aiht.2016.67.issue-4/aiht-2016-67-2795/aiht-2016-67-2795.xmlhttps://www.scopus.com/record/display.uri?eid=2-s2.0-85008698288&origin=SingleRecordEmailAlert&dgcid=scalert_sc_search_email&txGid=BCBFF82A73D51FA0ED62BC41FE5E598
https://radar.ibiss.bg.ac.rs/handle/123456789/2510