The pygidial gland secretion of the forest caterpillar hunter, Calosoma (Calosoma) sycophanta: the antimicrobial properties against human pathogens
2017
Autori:
Nenadić, MarijaSoković, Marina
Glamočlija, Jasmina
Ćirić, Ana
Perić Mataruga, Vesna
Ilijin, Larisa
Tešević, Vele
Todosijević, Marina
Vujisić, Ljubodrag
Vesović, Nikola
Ćurčić, Srećko
Tip dokumenta:
Članak u časopisu (Objavljena verzija)
,
© 2017 Springer-Verlag Berlin Heidelberg
Metapodaci
Prikaz svih podataka o dokumentuApstrakt:
Recently, various insect secretions have been tested as possible antimicrobial agents. In beetles, these secretions are essentially products of various exocrine glands, of which particular emphasis is on pygidial glands that are common for the suborder Adephaga. The antimicrobial potential of the pygidial gland secretion isolated from the adults of Calosoma sycophanta against human pathogens has been tested and compared with the potential of other carabid species, particularly within the tribe Carabini. The antimicrobial assay includes a microdilution method which was applied in order to determine the minimal inhibitory, minimal fungicidal and minimal bactericidal concentrations. It has been tested the effect of the secretion against eight strains of fungal and eight strains of bacterial species. The secretion sample of the tested carabid species has shown statistically significant antifungal effect against all strains of treated micromycetes, the highest in comparison with previously tested carabids (Carabus spp., Laemostenus punctatus and Abax parallelepipedus). Aspergillus versicolor proved to be the most sensitive micromycete, while the remaining seven fungal strains have shown the same level of sensibility. In comparison with commercial mycotics ketoconazole and bifonazole, applied as positive controls, the tested secretion showed much higher antifungal activity for all fungal strains. Antibacterial effect has been manifested only against one bacterial strain (Escherichia coli), contrary to other previously studied carabid species. These observations might have a significant impact on the ecological domain and possible purpose in biomedical studies and applications in the future. Additionally, morpho-histology of the pygidial glands of C. sycophanta is investigated and discussed.
Ključne reči:
Carabidae; Calosoma sycophanta; Antimicrobial activity; Microdilution; Morpho-histology; Pygidial gland secretionIzvor:
Applied Microbiology and Biotechnology, 2017, 101, 3, 977-985Finansiranje / projekti:
- Ontogenetska karakterizacija filogenije bioraznovrsnosti (RS-MESTD-Basic Research (BR or ON)-173038)
- Karakterizacija i primena metabolita gljiva i utvrđivanje potencijala novih biofungicida (RS-MESTD-Basic Research (BR or ON)-173032)
- Uticaj magnetnih polja i drugih sredinskih stresora na fiziološke odgovore i ponašanje različitih vrsta (RS-MESTD-Basic Research (BR or ON)-173027)
- Bioaktivni prirodni proizvodi samoniklih, gajenih i jestivih biljaka: određivanje struktura i aktivnosti (RS-MESTD-Basic Research (BR or ON)-172053)
DOI: 10.1007/s00253-016-8082-7
ISSN: 0175-7598
PubMed: 28070663
WoS: 000392502600006
Scopus: 2-s2.0-85008708376
URI
http://link.springer.com/10.1007/s00253-016-8082-7https://www.scopus.com/record/display.uri?eid=2-s2.0-85008708376&origin=SingleRecordEmailAlert&dgcid=scalert_sc_search_email&txGid=BCBFF82A73D51FA0ED62BC41FE5E5987.wsnAw8kcdt7IPYLO0V48gA%3A37
https://radar.ibiss.bg.ac.rs/handle/123456789/2511