Breast dynamic contrast enhanced MRI: fibrocystic changes presenting as a non-mass enhancement mimicking malignancy
2017
Аутори:
Milošević, Zorica C.Nadrljanski, Mirjan M.
Milovanović, Zorka M.
Gušić, Nina Z.
Vučićević, Slavko S.
Radulović, Olga
Тип документа:
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт:
We aimed to analyse the morphokinetic features of breast fibrocystic changes (nonproliferative lesions, proliferative lesions without atypia and proliferative lesions with atypia) presenting as a non-mass enhancement (NME)in dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) examination. Forty-six patients with histologically proven fibrocystic changes (FCCs) were retrospectively reviewed, according to Breast Imaging Reporting and Data System (BI-RADS) lexicon. Prior to DCE-MRI examination, a unilateral breast lesion suspicious of malignancy was detected clinically, on mammography or breast ultrasonography. The predominant features of FCCs presenting as NME in DCE-MRI examination were: unilateral regional or diffuse distribution (in 35 patients or 76.1%), heterogeneous or clumped internal pattern of enhancement (in 36 patients or 78.3%), plateau time-intensity curve (in 25 patients or 54.3%), moderate or fast wash-in (in 31 patients or 67.4%).Nonproliferative lesions were found in 11 patients (24%), proliferative lesions without atypia in 29 patients (63%) and lesions with atypia in six patients (13%), without statistically significant difference of morphokinetic features, except of the association of clustered microcysts with proliferative dysplasia without atypia. FCCs presenting as NME in DCE-MRI examination have several morphokinetic features suspicious of malignancy, therefore requiring biopsy (BI-RADS 4). Nonproliferative lesions, proliferative lesions without atypia and proliferative lesions with atypia predominantly share the same predefined DCE-MRI morphokinetic features.
Кључне речи:
Bbreast; Magnetic resonance imaging; Fibrocystic changesИзвор:
Radiology and Oncology, 2017, 51, 2, 130-136
DOI: 10.1515/raon-2017-0016
ISSN: 1318-2099
PubMed: 28740447
WoS: 000401697000002
Scopus: 2-s2.0-85020436866
URI
http://www.degruyter.com/view/j/raon.2017.51.issue-2/raon-2017-0016/raon-2017-0016.xmlhttps://radar.ibiss.bg.ac.rs/handle/123456789/2781