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Breast dynamic contrast enhanced MRI: fibrocystic changes presenting as a non-mass enhancement mimicking malignancy
dc.creator | Milošević, Zorica C. | |
dc.creator | Nadrljanski, Mirjan M. | |
dc.creator | Milovanović, Zorka M. | |
dc.creator | Gušić, Nina Z. | |
dc.creator | Vučićević, Slavko S. | |
dc.creator | Radulović, Olga | |
dc.date.accessioned | 2017-11-23T11:29:25Z | |
dc.date.available | 2017-11-23T11:29:25Z | |
dc.date.issued | 2017 | |
dc.identifier.issn | 1318-2099 | |
dc.identifier.uri | http://www.degruyter.com/view/j/raon.2017.51.issue-2/raon-2017-0016/raon-2017-0016.xml | |
dc.identifier.uri | https://radar.ibiss.bg.ac.rs/handle/123456789/2781 | |
dc.description.abstract | We aimed to analyse the morphokinetic features of breast fibrocystic changes (nonproliferative lesions, proliferative lesions without atypia and proliferative lesions with atypia) presenting as a non-mass enhancement (NME)in dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) examination. Forty-six patients with histologically proven fibrocystic changes (FCCs) were retrospectively reviewed, according to Breast Imaging Reporting and Data System (BI-RADS) lexicon. Prior to DCE-MRI examination, a unilateral breast lesion suspicious of malignancy was detected clinically, on mammography or breast ultrasonography. The predominant features of FCCs presenting as NME in DCE-MRI examination were: unilateral regional or diffuse distribution (in 35 patients or 76.1%), heterogeneous or clumped internal pattern of enhancement (in 36 patients or 78.3%), plateau time-intensity curve (in 25 patients or 54.3%), moderate or fast wash-in (in 31 patients or 67.4%).Nonproliferative lesions were found in 11 patients (24%), proliferative lesions without atypia in 29 patients (63%) and lesions with atypia in six patients (13%), without statistically significant difference of morphokinetic features, except of the association of clustered microcysts with proliferative dysplasia without atypia. FCCs presenting as NME in DCE-MRI examination have several morphokinetic features suspicious of malignancy, therefore requiring biopsy (BI-RADS 4). Nonproliferative lesions, proliferative lesions without atypia and proliferative lesions with atypia predominantly share the same predefined DCE-MRI morphokinetic features. | en |
dc.rights | openAccess | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.source | Radiology and Oncology | |
dc.subject | Bbreast | |
dc.subject | Magnetic resonance imaging | |
dc.subject | Fibrocystic changes | |
dc.title | Breast dynamic contrast enhanced MRI: fibrocystic changes presenting as a non-mass enhancement mimicking malignancy | en |
dc.type | article | |
dc.rights.license | BY-NC-ND | |
dcterms.abstract | Гушић, Нина З.; Радуловић, Олга С.; Миловановић, Зорка М.; Надрљански, Мирјан М.; Вучићевић, Славко С.; Милошевић, Зорица Ц.; | |
dc.rights.holder | © 2017 Radiol Oncol. | |
dc.citation.issue | 2 | |
dc.citation.volume | 51 | |
dc.identifier.doi | 10.1515/raon-2017-0016 | |
dc.identifier.pmid | 28740447 | |
dc.identifier.scopus | 2-s2.0-85020436866 | |
dc.identifier.wos | 000401697000002 | |
dc.citation.apa | Milosevic, Z. C., Nadrljanski, M. M., Milovanovic, Z. M., Gusic, N. Z., Vucicevic, S. S., & Radulovic, O. S. (2017). Breast dynamic contrast enhanced MRI: fibrocystic changes presenting as a non-mass enhancement mimicking malignancy. Radiology and Oncology, 51(2), 130–136. | |
dc.citation.vancouver | Milosevic ZC, Nadrljanski MM, Milovanovic ZM, Gusic NZ, Vucicevic SS, Radulovic OS. Breast dynamic contrast enhanced MRI: fibrocystic changes presenting as a non-mass enhancement mimicking malignancy. Radiol Oncol. 2017;51(2):130–6. | |
dc.citation.spage | 130 | |
dc.citation.epage | 136 | |
dc.type.version | publishedVersion | en |
dc.identifier.fulltext | https://radar.ibiss.bg.ac.rs/bitstream/id/3362/bitstream_3362.pdf | |
dc.citation.rank | M22 |