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Synthesis, characterization and cytotoxicity of a new palladium(II) complex with a coumarin-derived ligand 3-(1-(3-hydroxypropylamino)ethylidene)chroman-2,4-dione. Crystal structure of the 3-(1-(3-hydroxypropylamino)ethylidene)-chroman-2,4-dione
dc.creator | Avdović, Edina H. | |
dc.creator | Stojković, Danijela L.J. | |
dc.creator | Jevtić, Verica V. | |
dc.creator | Kosić, Milica | |
dc.creator | Ristić, Biljana | |
dc.creator | Harhaji-Trajković, Ljubica | |
dc.creator | Vukić, Milena | |
dc.creator | Vuković, Nenad | |
dc.creator | Marković, Zoran S. | |
dc.creator | Potočňák, Ivan | |
dc.creator | Trifunović, Srećko R. | |
dc.date.accessioned | 2017-11-23T11:28:44Z | |
dc.date.available | 2900-01-01 | |
dc.date.issued | 2017 | |
dc.identifier.issn | 0020-1693 | |
dc.identifier.uri | http://linkinghub.elsevier.com/retrieve/pii/S0020169317301597 | |
dc.identifier.uri | https://radar.ibiss.bg.ac.rs/handle/123456789/2792 | |
dc.description.abstract | The new coumarine derivative, 3-(1-(3-hydroxypropylamino)ethylidene)chroman-2,4-dione, and corresponding palladium(II) complex have been synthesized and characterized by microanalysis, infrared, 1H and 13C NMR spectroscopy. The structure of the ligand, solved using a monocrystal X-ray structural analysis, consists of two crystallographic different pseudocentrosymmetrically related molecules of 3-(1-(3-hydroxypropylamino)ethylidene)chroman-2,4-dione, while the structure of the square-planar palladium(II) complex was proposed on the basis of DFT calculations. The palladium(II) complex decreased viability of U251 human glioma and B16 mouse melanoma cells in a dose and time dependent manner, while its ligand exhibited only moderate cytotoxicity. | en |
dc.relation | info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172016/RS// | |
dc.relation | info:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/41010/RS// | |
dc.relation | info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172021/RS// | |
dc.relation | info:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/41025/RS// | |
dc.relation | info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173053/RS// | |
dc.relation | Bilateral project between Republic of Serbia and Slovak Republic No. SK-SRB-2013-0004 | |
dc.relation | Project VEGA No. 1/0598/14 | |
dc.rights | restrictedAccess | |
dc.source | Inorganica Chimica Acta | |
dc.subject | Coumarine-derived ligand | |
dc.subject | Palladium(II) complex | |
dc.subject | Cytotoxicity | |
dc.subject | Crystal structure | |
dc.subject | Apoptosis | |
dc.subject | Oxidative stress | |
dc.title | Synthesis, characterization and cytotoxicity of a new palladium(II) complex with a coumarin-derived ligand 3-(1-(3-hydroxypropylamino)ethylidene)chroman-2,4-dione. Crystal structure of the 3-(1-(3-hydroxypropylamino)ethylidene)-chroman-2,4-dione | en |
dc.type | article | |
dc.rights.license | ARR | |
dcterms.abstract | Хархаји Трајковић, Љубица; Aвдовић, Едина Х.; Стојковић, Данијела Л.Ј.; Трифуновић, Срећко Р.; Поточňáк, Иван; Марковић, Зоран С.; Вукић, Милена; Вуковић, Ненад; Косић, Милица; Ристић, Биљана; Јевтић, Верица В.; | |
dc.rights.holder | © 2017 Elsevier B.V. | |
dc.citation.volume | 466 | |
dc.description.other | Inorganica Chimica Acta (2017), 466: 188-196 | |
dc.identifier.doi | 10.1016/j.ica.2017.06.015 | |
dc.identifier.scopus | 2-s2.0-85020718781 | |
dc.identifier.wos | 000410683500024 | |
dc.citation.apa | Avdović, E. H., Stojković, D. L. J., Jevtić, V. V., Kosić, M., Ristić, B., Harhaji-Trajković, L., Vukić, M., et al. (2017). Synthesis, characterization and cytotoxicity of a new palladium(II) complex with a coumarin-derived ligand 3-(1-(3-hydroxypropylamino)ethylidene)chroman-2,4-dione. Crystal structure of the 3-(1-(3-hydroxypropylamino)ethylidene)-chroman-2,4-dione. Inorganica Chimica Acta, 466, 188–196. | |
dc.citation.vancouver | Avdović EH, Stojković DLJ, Jevtić V V., Kosić M, Ristić B, Harhaji-Trajković L, Vukić M, Vuković N, Marković ZS, Potočňák I, Trifunović SR. Synthesis, characterization and cytotoxicity of a new palladium(II) complex with a coumarin-derived ligand 3-(1-(3-hydroxypropylamino)ethylidene)chroman-2,4-dione. Crystal structure of the 3-(1-(3-hydroxypropylamino)ethylidene)-chroman-2,4-dione. Inorganica Chim Acta. 2017;466:188–96. | |
dc.citation.spage | 188 | |
dc.citation.epage | 196 | |
dc.type.version | publishedVersion | en |
dc.citation.rank | M22 |