Influence of radiation dose in computed tomography on antioxidant enzyme activity in rabbit erythrocytes
2017
Аутори:
Mitrović, Marko B.Ciraj-Bjelac, Olivera F.
Oreščanin Dušić, Zorana
Blagojević, Duško
Nikolić-Kokić, Aleksandra
Tatalović, Nikola
Krstić, Nikola E.
Lazarević-Macanović, Mirjana V.
Тип документа:
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт:
The objective of this study was to assess the radiation dose in computed tomography examinations of rabbits using different examination protocols and to correlate these values with the activity of antioxidant enzymes in their red blood cells following irradiation. The presented results revealed that a single, routine computed tomography scan exposure led to a different response of the activity of antioxidant enzymes in red blood cells regarding both dose and time. The results indicate that there is a dose threshold that is about 25 mGy. Doses below that level do not produce any significant changes in the level of antioxidant enzymes activity. On the other hand, the level just above that threshold had a significant impact on the antioxidant defence, but in a relatively short time period (2 hours after exposure), compared to the higher dose that requires a longer adaptive period.
Кључне речи:
Computed tomography; CT dose index; Erythrocyte; Antioxidant enzyme; RabbitИзвор:
Nuclear Technology and Radiation Protection, 2017, 32, 4, 342-349Финансирање / пројекти:
- Молекуларни механизми редокс сигналинга у хомеостази, адаптацији и патологији (RS-MESTD-Basic Research (BR or ON)-173014)
DOI: 10.2298/NTRP1704342M
ISSN: 1451-3994
WoS: 000423779500005
Scopus: 2-s2.0-85041126436
URI
http://ntrp.vinca.rs/2017_4/Mitrovic2017_4.htmlhttps://radar.ibiss.bg.ac.rs/handle/123456789/2967