What is the Impact of Epstein-Barr Virus in Peri-implant Infection?
2018
Autori:
Canullo, LuigiPesce, Paolo
Botticelli, Daniele
Covani, Ugo
Janković, Saša
Jovanović, Tanja
Rakić, Mia
Tip dokumenta:
Članak u časopisu (Objavljena verzija)
,
© 2018 by Quintessence Publishing Co Inc.
Metapodaci
Prikaz svih podataka o dokumentuApstrakt:
PURPOSE To compare the qualitative and quantitative profile of Epstein-Barr virus (EBV) at external and internal implant surfaces between participants with peri-implantitis and healthy peri-implant tissues and to quantitatively assess the relation between EBV and periopathogens inside the microbiologic profile associated with peri-implantitis. MATERIALS AND METHODS Microbiologic specimens were retrieved from 84 patients wearing 190 implants to estimate the levels of EBV and 10 periopathogens in the peri-implant pocket and internal-implant connection using quantitative polymerase chain reaction. RESULTS The study sample consisted of 113 healthy and 77 peri-implantitis-affected implants. Statistical significance was not reached in EBV prevalence between peri-implantitis and healthy controls. EBV-positive participants demonstrated higher levels of Prevotella intermedia (Pi) and Campylobacter rectus (Cr) compared with EBV-negative participants. A positive correlation was demonstrated among EBV and Tannerella forsythia (Tf), Parvimonas micra (Pm), Fusobacterium nucleatum (Fn), and Cr levels in peri-implantitis-affected implants, while healthy controls demonstrated a positive correlation between EBV and Aggregatibacter actinomycetemcomitans (Aa), Pi, and Pm. CONCLUSION EBV cannot be considered as a microbiologic marker of peri-implantitis. However, EBV could be considered as a risk factor and a peri-implantitis enhancer based on its positive correlations with pathogens associated with peri-implantitis.
Ključne reči:
Campylobacter rectus; Epstein-Barr virus infections; Fusobacterium nucleatum; Peri-implantitis; Prevotella intermediaIzvor:
The International Journal of Oral and Maxillofacial Implants, 2018, 33, 1, 58-63Finansiranje / projekti:
- Interakcija etiopatogenetskih mehanizama parodontopatije i paeriimplantitisa sa sistemskim bolestima današnjice (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-41008)
- Plastičnost mozga tokom starenja: uticaj dijetalne restrikcije i anestezije (RS-MESTD-Basic Research (BR or ON)-173056)
DOI: 10.11607/jomi.5972
ISSN: 0882-2786
PubMed: 29340343
WoS: 000424190000008
Scopus: 2-s2.0-85041856928
URI
http://quintpub.com/journals/omi/abstract.php?iss2_id=1499&article_id=17993https://radar.ibiss.bg.ac.rs/handle/123456789/3002