Laserpitium ochridanum: antioxidant, antimicrobial and anti-quorum sensing activities against Pseudomonas aeruginosa
2017
Аутори:
Mileski, Ksenija SlaveĆirić, Ana
Petrović, Jovana
Ristić, Mihailo S
Matevski, Vlado S
Marin, Petar D
Džamić, Ana M.
Тип документа:
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт:
This study shows Laserpitium ochridanum essential oil composition, its antifungal potency, and possible antioxidant, antimicrobial and anti-quorum sensing activities of different extracts. Monoterpene hydrocarbons (40.9%) found to be the most abundant group of constituents in the oil. Sabinene (22.8%), viridiflorol (14.7%) and α-pinene (11.40%) were the main compounds of the oil. Ethanolic extract had the highest antioxidant capacity in DPPH and ABTS assays and was the richest in polyphenols. Microdilution method revealed the strongest antibacterial activity of ethanolic extracts in comparison to other tested extracts and streptomycin. L. ochridanum oil evidenced the best antifungal potential against used micromycetes. Results of anti-quorum sensing activity assay indicated high affection of aqueous extract in reduction of PAO1 pyocianin production (18.07%).Used samples possessed slight reduction of twitching and swimming mobility. Excellent antifungal oil activity, good antioxidant, antimicrobial and anti-quorum activity of L. ochridanum extracts was found. This study shows for the first time anti-guorum sensing activity against Pseudomonas aeruginosa of L. ochridanum, as well as its significant antioxidant potential. This study was conducted due to adventives of usage of natural products as efficient substitution for synthetic agents in treatment of various medical conditions.
Кључне речи:
Antimicrobial activity; Antioxidant activity; Essential oil; Laserpitium ochridanum; Anti-quorum sensing activityИзвор:
Journal of Applied Botany and Food Quality, 2017, 90, 330-338Финансирање / пројекти:
- Микроморфолошка, фитохемијска и молекуларна истраживања биљака - систематски, еколошки и применљиви аспекти (RS-173029)
- Карактеризација и примена метаболита гљива и утврђивање потенцијала нових биофунгицида (RS-173032)
DOI: 10.5073/jabfq.2017.090.041
ISSN: 1439-040X
WoS: 000422847400001
Scopus: 2-s2.0-85044659951
URI
https://ojs.openagrar.de/index.php/JABFQ/article/view/6507https://radar.ibiss.bg.ac.rs/handle/123456789/3031