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Prooxidant effects of chronic exposure to deltamethrin in green toad Bufotes viridis.
dc.creator | Nasia, Mohammed M. | |
dc.creator | Radovanović, Tijana | |
dc.creator | Krizmanić, Imre I. | |
dc.creator | Prokić, Marko | |
dc.creator | Gavrić, Jelena | |
dc.creator | Despotović, Svetlana | |
dc.creator | Gavrilović, Branka | |
dc.creator | Borković Mitić, Slavica | |
dc.creator | Pavlović, Slađan | |
dc.creator | Saičić, Zorica | |
dc.date.accessioned | 2018-10-03T09:43:16Z | |
dc.date.available | 2900-01-01 | |
dc.date.issued | 2018 | |
dc.identifier.uri | http://link.springer.com/10.1007/s11356-018-2979-x | |
dc.identifier.uri | https://radar.ibiss.bg.ac.rs/handle/123456789/3142 | |
dc.description.abstract | Pesticide-induced oxidative stress, as one of mechanism of toxicity, has been a focus of toxicological research. However, there is a lack of data for certain pesticides-oxidative stress effects especially on terrestrial amphibians. This study evaluates the prooxidative effects of orally administered insecticide deltamethrin (DM) in some tissues of the terrestrial toad Bufotes viridis. Toads were randomly divided and assigned to a control group and a test group that was orally exposed to the pesticide (5 mg/kg of body weight/daily) for 21 days. Animals were euthanized from each group on days 7, 14, and 21, and the liver, leg muscle, ventral skin, and gastrointestinal tissue (GIT) were dissected and used for analysis. From battery of investigated antioxidant components, superoxide dismutase (SOD) was the most differentiate parameter in all examined tissues. For the period of prolonged exposure to pesticide, antioxidative strategy of Bufotes viridis was based on SOD utilization in attempt to maintain the oxidative disbalance at acceptable level. The integrated biomarker response (IBR) as the measure of the overall biochemical response to DM exposure revealed that the group exposed for 21 days had the highest response. Our work has offered valuable data ensuring evidence that toads exposed to deltamethrin developed adaptive reactions that were tissue-specific and that DM-generated systemic toxicity was time-dependent. The present work showed that oxidative stress has significant role in pesticide-induced toxicity and contributes to better understanding of ecotoxicological risk in the terrestrial amphibians exposed to DM. | en |
dc.relation | info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173041/RS// | |
dc.rights | restrictedAccess | |
dc.source | Environmental Science and Pollution Research International | |
dc.subject | Biomarkers | |
dc.subject | Bufotes viridis | |
dc.subject | Chronic exposure | |
dc.subject | Deltamethrin | |
dc.subject | Oxidative stress | |
dc.subject | Pyrethroid | |
dc.subject | Sublethal exposure | |
dc.title | Prooxidant effects of chronic exposure to deltamethrin in green toad Bufotes viridis. | en |
dc.type | article | en |
dc.rights.license | ARR | |
dcterms.abstract | Саичић, Зорица; Радовановић, Тијана; Кризманић, Имре И.; Гаврић, Јелена; Деспотовић, Светлана; Гавриловић, Бранка; Павловић, Слађан; Насиа, Мохаммед М.; Прокић, Марко; Борковић-Митић, Славица С.; | |
dc.rights.holder | © 2018, Springer-Verlag GmbH Germany, part of Springer Nature. | |
dc.citation.issue | 30 | |
dc.citation.volume | 25 | |
dc.identifier.doi | 10.1007/s11356-018-2979-x | |
dc.identifier.pmid | 30173389 | |
dc.identifier.scopus | 2-s2.0-85053277482 | |
dc.identifier.wos | 000446844400075 | |
dc.citation.apa | Nasia, M. M., Radovanović, T. B., Krizmanić, I. I., Prokić, M. D., Gavrić, J. P., Despotović, S. G., et al. (2018). Prooxidant effects of chronic exposure to deltamethrin in green toad Bufotes viridis. Environmental Science and Pollution Research International, 25(30), 30597–30608. | |
dc.citation.vancouver | Nasia MM, Radovanović TB, Krizmanić II, Prokić MD, Gavrić JP, Despotović SG, Gavrilović BR, Borković-Mitić SS, Pavlović SZ, Saičić ZS. Prooxidant effects of chronic exposure to deltamethrin in green toad Bufotes viridis. Environ Sci Pollut Res Int. 2018;25(30):30597–608. | |
dc.citation.spage | 30597 | |
dc.citation.epage | 30608 | |
dc.type.version | publishedVersion | |
dc.citation.rank | M22 |