Study of genotoxicity and antigenotoxicity of the Cotinus coggygria Scop. methanol extract by Drosophila melanogaster sex-linked recessive lethal test.
2011
Autori:
Stanić, SnežanaMatić, Sanja
Đelić, Gorica
Mihailović, Mirjana
Bogojević, Desanka
Solujić, Slavica
Tip dokumenta:
Članak u časopisu (Objavljena verzija)
,
© 2011, Pleiades Publishing, Ltd.
Metapodaci
Prikaz svih podataka o dokumentuApstrakt:
The genotoxic and antigenotoxic effects of Cotinus coggygria Scop. methanol extract was investigated using the Drosophila sex-linked recessive lethal (or SLRL) test. The results presented here show that the methanol extract of Cotinus coggygria in a concentration of 5% and artificial chemical agent ethyl methanesulfonate EMS (0.75 ppm) induce recessive lethal mutations on X-chromosome on Drosophila melanogaster in all broods (I, II and III). Post-treatment with lower concentration of the methanol extract of Cotinus coggygria (2%) was effective in reducing genotoxicity ofmutagen.
Ključne reči:
Gallic Acid; Methanol Extract; Oleu Ropein; Ethyl Methane Sulfonate; Methyl GallateIzvor:
Russian Journal of Genetics, 2011, 47, 7, 770-774
DOI: 10.1134/S1022795411070167
ISSN: 1022-7954
PubMed: 21938950