Chemical features of Ganoderma polysaccharides with antioxidant, antitumor and antimicrobial activities
2015
Аутори:
Ferreira, Isabel C. F. R.Heleno, Sandrina A.
Reis, Filipa S.
Stojković, Dejan
Queiroz, Maria Joao R. P.
Helena Vasconcelos, M.
Soković, Marina
Тип документа:
Приказ (Рецензирана верзија)
Метаподаци
Приказ свих података о документуАпстракт:
Ganoderma genus comprises one of the most commonly studied species worldwide, Ganoderma lucidum. However, other Ganoderma species have been also reported as important sources of bioactive compounds. Polysaccharides are important contributors to the medicinal properties reported for Ganoderma species, as demonstrated by the numerous publications, including reviews, on this matter. Yet, what are the chemical features of Ganoderma polysaccharides that have bioactivity? In the present manuscript, the chemical features of Ganoderma polysaccharides with reported antioxidant, antitumor and antimicrobial activities (the most studied worldwide) are analyzed in detail. The composition of sugars (homo- versus hetero-glucans and other polysaccharides), type of glycosidic linkages, branching patterns, and linkage to proteins are discussed. Methods for extraction, isolation and identification are evaluated and, finally, the bioactivity of polysaccharidic extracts and purified compounds are discussed. The integration of data allows deduction of structure-activity relationships and gives clues to the chemical aspects involved in Ganoderma bioactivity. (C) 2014 Elsevier Ltd. All rights reserved.
Напомена:
This is the peer reviewed version of the following article: Ferreira ICFR, Heleno SA, Reis FS, Stojkovic D, Queiroz MJRP, Vasconcelos MH, Sokovic M. Chemical features of Ganoderma polysaccharides with antioxidant, antitumor and antimicrobial activities. Phytochemistry. 2015;114:38–55. http://dx.doi.org/10.1016/j.phytochem.2014.10.011
Кључне речи:
Ganoderma; Polysaccharides; Chemical features; Bioactivity; Structure-activityИзвор:
Phytochemistry, 2015, 114, SI, 38-55
DOI: 10.1016/j.phytochem.2014.10.011
ISSN: 0031-9422
PubMed: 25457487
WoS: 000356551800005
Scopus: 2-s2.0-84929709160
URI
https://radar.ibiss.bg.ac.rs/handle/123456789/1948https://radar.ibiss.bg.ac.rs/handle/123456789/3526