Complete mitogenome data for the Serbian population: the contribution to high-quality forensic databases.
2020
Аутори:
Davidović, SlobodanMalyarchuk, Boris
Grzybowski, Tomasz
Aleksić, Jelena M.
Derenko, Miroslava
Litvinov, Andrey
Rogalla-Ładniak, Urszula
Stevanović, Milena
Kovačević-Grujičić, Nataša
Тип документа:
Чланак у часопису (Рецензирана верзија)
,
© 2020 Springer Nature Switzerland AG. Part of Springer Nature.
Метаподаци
Приказ свих података о документуАпстракт:
Mitochondrial genome (mtDNA) is a valuable resource in resolving various human forensic casework. The usage of variability of complete mtDNA genomes increases their discriminatory power to the maximum and enables ultimate resolution of distinct maternal lineages. However, their wider employment in forensic casework is nowadays limited by the lack of appropriate reference database. In order to fill in the gap in the reference data, which, considering Slavic-speaking populations, currently comprises only mitogenomes of East and West Slavs, we present mitogenome data for 226 Serbians, representatives of South Slavs from the Balkan Peninsula. We found 143 (sub)haplogroups among which West Eurasian ones were dominant. The percentage of unique haplotypes was 85%, and the random match probability was as low as 0.53%. We support previous findings on both high levels of genetic diversity in the Serbian population and patterns of genetic differentiation among this and ten studied European populations. However, our high-resolution data supported more pronounced genetic differentiation among Serbians and two Slavic populations (Russians and Poles) as well as expansion of the Serbian population after the Last Glacial Maximum and during the Migration period (fourth to ninth century A.D.), as inferred from the Bayesian skyline analysis. Phylogenetic analysis of haplotypes found in Serbians contributed towards the improvement of the worldwide mtDNA phylogeny, which is essential for the interpretation of the mtDNA casework.
Кључне речи:
Complete mitogenomes; Demographic changes; Molecular phylogeography; Serbian populationИзвор:
International Journal of Legal Medicine, 2020, 134, 1581-1590Финансирање / пројекти:
- Ministry of Education, Science and Technological Development, Republic of Serbia (grant no. 47025 and agreement no. 451-03-68/2020-14/200042)
- Russian Foundation for Basic Research (grant numbers 14-04-00131 and 16-34-00014)
DOI: 10.1007/s00414-020-02324-x
ISSN: 0937-9827
PubMed: 32504149
WoS: 000538242000001
Scopus: 2-s2.0-85086108468
URI
http://link.springer.com/10.1007/s00414-020-02324-xhttp://www.ncbi.nlm.nih.gov/pubmed/32504149
https://radar.ibiss.bg.ac.rs/handle/123456789/3685