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Short- and Long-Term Exposure to Alternating Magnetic Field (50 Hz, 0.5 mT) Affects Rat Pituitary ACTH Cells: Stereological Study
dc.creator | Rauš Balind, Snežana | |
dc.creator | Manojlović-Stojanoski, Milica | |
dc.creator | Milošević, Verica | |
dc.creator | Todorović, Dajana | |
dc.creator | Nikolić, Ljiljana | |
dc.creator | Petković, Branka | |
dc.date.accessioned | 2020-07-16T08:44:54Z | |
dc.date.available | 2900-01-01 | |
dc.date.issued | 2016 | |
dc.identifier.issn | 1520-4081 | |
dc.identifier.issn | 1520-4081 | |
dc.identifier.uri | https://onlinelibrary.wiley.com/doi/abs/10.1002/tox.22059 | |
dc.identifier.uri | https://radar.ibiss.bg.ac.rs/handle/123456789/3776 | |
dc.description.abstract | The aim of the present study was to determine does extremely low frequency magnetic field (ELF-MF, 50 Hz, 0.5 mT) affect pituitary adrenocorticotroph (ACTH) cells in adult animals. We performed two series of experiments: (1) short-term exposure of 3-month-old rats to ELF-MF for 1 and 7 days, and (2) long-term exposure of rats to ELF-MF from their conception to 3 months of age. Stereological study was performed on immunolabeled pituitary ACTH cells. The total number and volume of ACTH cells, the volume of their nuclei and pituitary volume were measured. ELF-MF exposure for 1 day significantly decreased total number and volume of ACTH cells, the volume of their nuclei, as well as pituitary volume. ELF-MF exposure for 7 days significantly reduced only the volume of ACTH cells. Life-long exposure to ELF-MF induced decrease in the volume of ACTH cells and pituitary volume. We can conclude that the applied ELF-MF has a strong influence on morphometrical parameters of the pituitary ACTH cells and could be considered as a stressogenic factor. | en |
dc.language.iso | en | sr |
dc.publisher | John Wiley and Sons Inc. | sr |
dc.relation | info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173027/RS// | sr |
dc.rights | restrictedAccess | sr |
dc.source | Environmental Toxicology | sr |
dc.subject | Extremely low frequency magnetic field | sr |
dc.subject | ACTH cells | sr |
dc.subject | Stereology | sr |
dc.subject | Pituitary | sr |
dc.title | Short- and Long-Term Exposure to Alternating Magnetic Field (50 Hz, 0.5 mT) Affects Rat Pituitary ACTH Cells: Stereological Study | en |
dc.type | article | sr |
dc.rights.license | ARR | sr |
dcterms.abstract | Манојловић-Стојаноски, Милица; Рауш Балинд, Снежана; Милошевић, Верица; Тодоровић, Дајана; Николић, Љиљана; Петковић, Бранка; | |
dc.rights.holder | © 2014 Wiley Periodicals, Inc. | sr |
dc.citation.issue | 4 | |
dc.citation.volume | 31 | |
dc.identifier.doi | 10.1002/tox.22059 | |
dc.identifier.pmid | 25346405 | |
dc.identifier.scopus | 2-s2.0-84960472575 | |
dc.identifier.wos | 000372318300008 | |
dc.citation.spage | 461 | |
dc.citation.epage | 468 | |
dc.type.version | publishedVersion | sr |
dc.citation.rank | aM21 |