Antifungalna aktivnost etarskog ulja Valeriana officinalis L.

Abstract

In this paper essential oil of V. officinalis as potential antifungal agent was analyzed. Following micromycetes as test organisms were included: Penicillium ochrochloron, Alternaria alternata, Aureobasidium pullulans, Trichoderma viride, Cladosporium cladosporioides, Fulvia fulvium, Phomopsis helianthi and dermatomicetes Trichophyton rubrum, Trichophyton tonsurans, Epidermophyton floccosum i Microsporum canis. Throughout the macrodilution method on agar substrates, after incubation period, minimum inhibition concentration (MIC) was recorded. The concentration of 20 ml/ml showed fungistatic activity against T. viride. For species P. ochrochloron, A. alternata, A. pullulans MIC was 10 ml/ml, and for C. cladosporioides, F. fulvium and P. helianthi like for analyzed dermatomycetes MIC was 5 ml/ml. Further investigations will comprise larger number of testing fungi and examination of antifungal activities of single essential oil components of V. officinalis.

U ovom radu analizirano je etarsko ulje V. officinalis L. kao potencijalni antifungalni agens. Kao test organizmi korišćene su sledeće mikromicete: Penicillium ochrochloron, Alternaria alternata, Aureobasidium pullulans, Trichoderma viride, Cladosporium cladosporioides, Fulvia fulvium, Phomopsis helianthi i dermatomicete Trichophyton rubrum, Trichophyton tonsurans, Epidermophyton floccosum i Microsporum canis. Makrodilucionom metodom su na agarnim podlogama utvrđivane minimalne inhibitorne koncentracije (MIC). Koncentracija od 20 ml/ml pokazala je fungistatsku aktivnost na vrstu T. viride. Za vrste P. ochrochloron, A. alternata, A. pullulans MIC je 10 ml/ml, a za C. cladosporioides, F. fulvium i P. helianthi kao i za analizirane dermatomicete MIC iznosi 5ml/ml. Dalja istraživanja obuhvatiće veći broj testiranih gljiva i ispitivanje antifungalne aktivnosti pojedinačnih komponenti etarskog ulja V. officinalis.