Cadmium and immunologically-mediated homeostasis of anatomical barrier tissues
2021
Аутори:
Popov Aleksandrov, AleksandraMirkov, Ivana
Tucović, Dina
Kulaš, Jelena
Ninkov, Marina
Kataranovski, Milena
Тип документа:
Приказ (Објављена верзија)
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© 2020 Elsevier B.V.
Метаподаци
Приказ свих података о документуАпстракт:
Cadmium (Cd) is a toxic heavy metal that when absorbed into the body causes nephrotoxicity and effects in other tissues.Anatomical barrier tissues are tissues that prevent the entry of pathogens and include skin, mucus membranes and the immune system. The adverse effects of Cd-induced immune cell's activity are the most extensively studied in the kidneys and the liver. There are though fewer data relating the effect of this metal on the other tissues, particularly in those in which cells of the immune system form local circuits of tissue defense, maintaining immune-mediated homeostasis. In this work, data on the direct and indirect effects of Cd on anatomical barrier tissue of inner and outer body surfaces (the lungs, gut, reproductive organs, and skin) were summarized.
Кључне речи:
Barrier tissues; Cadmium; Immune systemИзвор:
Toxicology Letters, 2021, 337, 38-45Финансирање / пројекти:
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200007 (Универзитет у Београду, Институт за биолошка истраживања 'Синиша Станковић') (RS-MESTD-inst-2020-200007)
DOI: 10.1016/j.toxlet.2020.11.008
ISSN: 0378-4274
PubMed: 33246043