Cadmium and immunologically-mediated homeostasis of anatomical barrier tissues
2021
Autori:
Popov Aleksandrov, AleksandraMirkov, Ivana
Tucović, Dina
Kulaš, Jelena
Ninkov, Marina
Kataranovski, Milena
Tip dokumenta:
Prikaz (Objavljena verzija)
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© 2020 Elsevier B.V.
Metapodaci
Prikaz svih podataka o dokumentuApstrakt:
Cadmium (Cd) is a toxic heavy metal that when absorbed into the body causes nephrotoxicity and effects in other tissues.Anatomical barrier tissues are tissues that prevent the entry of pathogens and include skin, mucus membranes and the immune system. The adverse effects of Cd-induced immune cell's activity are the most extensively studied in the kidneys and the liver. There are though fewer data relating the effect of this metal on the other tissues, particularly in those in which cells of the immune system form local circuits of tissue defense, maintaining immune-mediated homeostasis. In this work, data on the direct and indirect effects of Cd on anatomical barrier tissue of inner and outer body surfaces (the lungs, gut, reproductive organs, and skin) were summarized.
Ključne reči:
Barrier tissues; Cadmium; Immune systemIzvor:
Toxicology Letters, 2021, 337, 38-45Finansiranje / projekti:
- Ministarstvo nauke, tehnološkog razvoja i inovacija Republike Srbije, institucionalno finansiranje - 200007 (Univerzitet u Beogradu, Institut za biološka istraživanja 'Siniša Stanković') (RS-MESTD-inst-2020-200007)
DOI: 10.1016/j.toxlet.2020.11.008
ISSN: 0378-4274
PubMed: 33246043