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Phenolic compounds and biopotential of grape pomace extracts from Prokupac red grape variety
dc.creator | Milinčić, Danijel D. | |
dc.creator | Stanisavljević, Nemanja S. | |
dc.creator | Kostić, Aleksandar | |
dc.creator | Soković Bajić, Svetlana | |
dc.creator | Kojić, Milan O. | |
dc.creator | Gašić, Uroš | |
dc.creator | Barać, Miroljub B. | |
dc.creator | Stanojević, Sladjana P. | |
dc.creator | Tešić, Živoslav Lj. | |
dc.creator | Pešić, Mirjana B. | |
dc.date.accessioned | 2021-01-15T10:47:28Z | |
dc.date.available | 2900-01-01 | |
dc.date.issued | 2021 | |
dc.identifier.issn | 0023-6438 | |
dc.identifier.uri | https://radar.ibiss.bg.ac.rs/handle/123456789/4092 | |
dc.description.abstract | Phenolic compounds and biopotential (antioxidant, cellular antioxidant and cytotoxic activity) of grape pomace (GP) skin, seed, stem and whole GP originating from indigenous red grape variety Prokupac were evaluated. The UHPLC-Orbitrap MS4 analysis showed the presence of 75 phenolic compounds (57 non-anthocyanins and 18 anthocyanins), among which considerable content of ethyl gallate was observed and malvidin-3-O-hexoside-(8,8)-methylmethyne-(epi)catechin was identified. The stem had significant content of stilbenoids. The GP seed and the whole GP showed the highest antioxidant activity estimated by ABTS•+ DPPH• and H2O2 scavenging assays that were strongly correlated with the presence of flavan-3-ols, phenolic acids and ethyl gallate. The GP skin exerted cellular antioxidant activity on adenocarcinoma cells (EC50 = 56.4 mg TPCs/mL) which was strongly correlated with the presence of flavonols and anthocyanins. These by-products of Prokupac red grape variety are a notable source of phenolic compounds with good antioxidant activity that can be extensively used in food and pharmaceutical industry. | |
dc.publisher | Academic Press | |
dc.relation | info:eu-repo/grantAgreement/MESTD/inst-2020/200007/RS// | |
dc.relation | info:eu-repo/grantAgreement/MESTD/inst-2020/200116/RS// | |
dc.relation | info:eu-repo/grantAgreement/MESTD/inst-2020/200042/RS// | |
dc.rights | restrictedAccess | |
dc.source | LWT | |
dc.source | LWT | |
dc.subject | Antioxidant activity | |
dc.subject | Cellular antioxidant activity | |
dc.subject | Cytotoxic activity | |
dc.subject | Phenolic compounds | |
dc.subject | Wine by-products | |
dc.title | Phenolic compounds and biopotential of grape pomace extracts from Prokupac red grape variety | |
dc.type | article | en |
dc.rights.license | ARR | |
dcterms.abstract | Станисављевић, Немања С.; Гашић, Урош; Соковић Бајић, Светлана; Бараћ, Мирољуб Б.; Станојевић, Сладјана П.; Тешић, Живослав Љ.; Костић, Aлександар; Милинчић, Данијел Д.; Којић, Милан О.; Пешић, Мирјана Б.; | |
dc.rights.holder | © 2020 Elsevier Ltd. | |
dc.citation.volume | 138 | |
dc.identifier.doi | 10.1016/j.lwt.2020.110739 | |
dc.identifier.scopus | 2-s2.0-85098179864 | |
dc.identifier.wos | 000608242300085 | |
dc.citation.apa | Milinčić, D. D., Stanisavljević, N. S., Kostić, A., Soković Bajić, S., Kojić, M. O., Gašić, U. M., et al. (2021). Phenolic compounds and biopotential of grape pomace extracts from Prokupac red grape variety. LWT, 138, 110739. | |
dc.citation.vancouver | Milinčić DD, Stanisavljević NS, Kostić A, Soković Bajić S, Kojić MO, Gašić UM, Barać MB, Stanojević SP, Lj Tešić Ž, Pešić MB. Phenolic compounds and biopotential of grape pomace extracts from Prokupac red grape variety. LWT. 2021;138:110739. | |
dc.citation.spage | 110739 | |
dc.type.version | publishedVersion | |
dc.citation.rank | M21 |