Possible zinc deficiency in the Serbian population: examination of body fluids, whole blood and solid tissues
2021
Аутори:
Jagodić, JovanaRovčanin, Branislav
Borković Mitić, Slavica
Vujotić, Ljiljana
Avdin, Viacheslav
Manojlović, Dragan
Stojsavljević, Aleksandar
Тип документа:
Чланак у часопису (Објављена верзија)
,
© 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
Метаподаци
Приказ свих података о документуАпстракт:
Studies indicate that the soil, water and consequently foodstuffs in Serbia are significantly poor in zinc (Zn), and thus, it is likely that there is a Zn deficiency in the Serbian population. This study examined the Zn status in multiple clinical samples, including body fluids (serum, cerebrospinal fluid), whole blood and Zn-rich solid tissues (thyroid and brain tissue). Differences between sex and age were also considered, and comparative analysis of Zn status with other world populations was performed. Serum samples from a large number of Serbian adults approximately had twofold lower Zn amounts when compared to other populations. A similar trend was obtained for whole blood. Males had significantly higher amounts of Zn in serum, whole blood and thyroid tissue samples than females. Higher amounts of Zn were observed in the group older than 50 years. Importantly, in thyroid and brain tissues, Zn was 10- and 20-fold lower, respectively, than reported in the literature. Our results indicate that the population in Serbia could be considered Zn deficient. Therefore, adequate oral Zn supplementation and/or foodstuff fortification should be considered to prevent the deleterious effects caused by Zn deficiency.
Кључне речи:
Body fluids; Brain tissue; Serbian population; Thyroid tissue; Whole blood; ZincИзвор:
Environmental Science and Pollution Research, 2021, 28, 34, 47439-47446Финансирање / пројекти:
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200288 (Иновациони центар Хемијског факултета у Београду доо) (RS-MESTD-inst-2020-200288)
DOI: 10.1007/s11356-021-14013-2
ISSN: 0944-1344
PubMed: 33893588