Are receptor tyrosine kinases chimeric AGP’s?
2018
Аутори:
Paunović, DanijelaBogdanović, Milica
Trifunović-Momčilov, Milana
Todorović, Slađana
Simonović, Ana
Subotić, Angelina
Dragićević, Milan
Остала ауторства
Uzelac, BrankaТип документа:
Конференцијски прилог (Објављена верзија)
,
© 2018 by the Serbian Plant Physiology Society
Метаподаци
Приказ свих података о документуАпстракт:
Arabinogalactan proteins (AGPs) are cell wall proteoglycans with important roles during plant
growth and development. They comprise one of the most complex families of macromolecules
found in plants, which is in part due to the incredible diversity of the glycans decorating the pro-
tein backbone, as well as the heterogeneity of the protein backbones. While this diversity is cer-
tainly responsible for the wide array of physiological functions associated with AGPs, it hampers
efforts for homology-based identification. We have developed a new method for filtering AGP se-
quences that exploits one of their key features, the presence of hydroxyprolines, which represent
glycosylation sites. This method was used to filter potential AGPs from Centaurium erythraea RNA-
seq data. Most of the filtered sequences had no identifiable domains, while the most frequent
identified domains were the Protein kinase and Protein tyrosine kinase domains identified in the
same sequences, followed by well-known AGP associates, Leucine rich repeats, Probable lipid
transfer, Plastocyanin-like and Fasciclin. It is noteworthy that the Protein (tyrosine) kinase domain
has thus far eluded experimental evidence for linkage with AGPs in any plant species, probably
due to its transmembrane nature. The implicated sequences were examined in depth and com-
pared to homologs from Arabidopsis.
Кључне речи:
arabinogalactan proteins; bioinformatics; hydroxyproline prediction; finding-AGPФинансирање / пројекти:
- Физиолошка, хемијска и молекуларна анализа диверзитета одабраних ретких и угрожених биљних врста у циљу еx ситу заштите и продукције биолошки активних једињења (RS-MESTD-Basic Research (BR or ON)-173024)
- Развој и примена биотехнолошких поступака у добијању здравог садног материјала украсних биљака (RS-MESTD-Technological Development (TD or TR)-31019)
У:
- Uzelac B, editor. Book of abstracts. 3rd International Conference on Plant Biology (22nd SPPS Meeting); 2018 Jun 9-12; Belgrade, Serbia. Belgrade: Serbian Plant Physiology Society; Institute for Biological Research "Siniša Stanković"; Faculty of Biology; 2018. p. 17.