Chemical composition and biological activity of cardoon (Cynara cardunculus L. var. altilis) seeds harvested at different maturity stages.
2021
Authors:
Mandim, FilipaPetropoulos, Spyridon A.
Pinela, José
Dias, Maria Inês
Giannoulis, Kyriakos D.
Kostić, Marina
Soković, Marina
Queijo, Beatriz
Santos-Buelga, Celestino
Ferreira, Isabel C F R
Barros, Lillian
Document Type:
Article (Published version)
,
© 2021 Elsevier Ltd.
Metadata
Show full item recordAbstract:
Cardoon seeds collected in Greece at four different maturity stages (samples S1 to S4) were analysed in terms of chemical composition and in vitro bioactivities. The content of phenolic compounds (six compounds in total) increased with increasing maturity, and 3,5-O-dicaffeyolquinic (14.8-33.8 mg/g extract) acid was the compound detected in higher abundance. Mature seeds (sample S4) also revealed the highest content in lipids (23 g/100 g extract) and tocopherols (29.62 mg/100 g dw) and demonstrated the highest cytotoxic (GI50 of 97-216 µg/mL) and anti-inflammatory (IC50 = 148 µg/mL) activities, and capacity to inhibit the formation of thiobarbituric acid reactive substances (TBARS) (IC50 = 5 µg/mL). Cardoon seed hydroethanolic extracts also revealed high antibacterial and antifungal potential, particularly samples S3 and S1, respectively. This study proved the multifaceted potential associated with valorisation of cardoon seeds, while their biological and chemical composition can be influenced by the maturity stage.
Keywords:
Bioactive properties; Cardoon seeds; Cynara cardunculus (L.); Cytotoxicity; Maturity stage; Phenolic compositionSource:
Food Chemistry, 2021, 369, 130875-Funding / projects:
- Ministry of Science, Technological Development and Innovation of the Republic of Serbia, institutional funding - 200007 (University of Belgrade, Institute for Biological Research 'Siniša Stanković') (RS-MESTD-inst-2020-200007)
DOI: 10.1016/j.foodchem.2021.130875
ISSN: 0308-8146
PubMed: 34438342
WoS: 000709484300008
Scopus: 2-s2.0-85113334031
URI
https://linkinghub.elsevier.com/retrieve/pii/S0308814621018811https://radar.ibiss.bg.ac.rs/handle/123456789/4474