Antimicrobial activity of Annona muricata leaf oleoresin.
2021
Аутори:
Cagnini, Caroline ZanellaDias, Angélica Barbosa
Vilas Boas, Mariana Rodrigues
Batista, Fabiana Pacheco Reis
Faria, Maria Graciela Iecher
Glamočlija, Jasmina
Soković, Marina
Tešević, Vele
Ferreira, Ederlan de Souza
Colauto, Nelson Barros
Linde, Giani Andrea
Gazim, Zilda Cristiani
Тип документа:
Чланак у часопису (Објављена верзија)
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© 2021 by the Taylor and Francis Ltd.
Метаподаци
Приказ свих података о документуАпстракт:
Bioactive compounds extracted from plants such as antimicrobials have attracted the attention of consumers and the food industry. This study aimed to determine the antimicrobial activity and chemical composition of Annona muricata leaf oleoresin obtained by supercritical CO2 extraction. The oleoresin was obtained by supercritical CO2 extraction and the chemical identification by gas chromatography coupled to mass spectrometry. Antimicrobial activity was evaluated by broth microdilution method against 14 foodborne fungi and bacteria. The oleoresin major chemical class was phytosterols (22.7%) and the major compounds were γ-sitosterol (15.7%), α-tocopherol (13.7%), phytol (13.1%), and hexadecanoic acid (11.5%). Minimum inhibitory concentration against bacteria ranged from 0.0025 to 0.010 mg mL-1. The oleoresin had high bactericidal activity against all bacteria, mainly Enterobacter cloacae and Pseudomonas aeruginosa with 0.005 mg mL-1 minimum bactericidal concentration. However, it had low fungicidal activity. The leaf oleoresin of A. muricata has promising applications in food, cosmetic, and pharmaceutical industries.
Кључне речи:
Annonaceae; Soursop; Bactericide; Food conservation; Natural product; Supercritical CO2Извор:
Natural product research, 2021Финансирање / пројекти:
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200007 (Универзитет у Београду, Институт за биолошка истраживања 'Синиша Станковић') (RS-MESTD-inst-2020-200007)
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200168 (Универзитет у Београду, Хемијски факултет) (RS-MESTD-inst-2020-200168)
- Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPQ)
DOI: 10.1080/14786419.2021.2011270
ISSN: 1478-6419
PubMed: 34866508