Hieracium waldsteinii (Asteraceae) and Onosma stellulata (Boraginaceae) as a Source of Antioxidant and Antimicrobial Agents.
2022
Аутори:
Kostić, Aleksandar Ž.Mačukanović-Jocić, Marina P
Milinčić, Danijel D.
Petrović, Jovana
Gašić, Uroš
Gligorijević, Nevenka N.
Jarić, Snežana
Soković, Marina
Tešić, Živoslav Lj.
Pešić, Mirjana B.
Тип документа:
Чланак у часопису (Објављена верзија)
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© 2022 Wiley-VHCA AG, Zurich, Switzerland
Метаподаци
Приказ свих података о документуАпстракт:
The current study aimed to phytochemically characterize (including a detailed phenolic profile) two endemic Balkan's species (Hieracium waldsteinii and Onosma stellulata) and determine their possible application as a source of natural antioxidant and antimicrobial agents. The main phenolic compound in both species (in all examined parts) was chlorogenic acid. Eriodictyol, genistein and naringenin were quantified only in H. waldsteinii while isorhamnetin-3-O-rutinoside and sinapic acid were characteristic for O. stellulata. The highest antioxidant activity (98 mg AAE/g dry weight for TAC assay) was ascribed to the flower extract of H. waldsteinii while the lowest results (∼4.3 mg AAE/g dry weight for FRP assay) were exhibited by the extracts obtained from the plant's stem. Antimicrobial assays showed moderate antibacterial, i. e., moderate/strong activity against several tested fungi (in particular Trichoderma viride). Correlation analysis revealed strong positive connection between phenolic compounds and reducing power of extracts as well as between total phenolic and flavonoid content and the obtained minimal inhibitory concentration recorded in antibacterial assays.
Кључне речи:
Hieracium waldsteinii; Onosma stellulata; Antimicrobial activity; Antioxidant properties; Phenolic compositionИзвор:
Chemistry & Biodiversity, 2022, 19, 4, e202200069-Финансирање / пројекти:
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200007 (Универзитет у Београду, Институт за биолошка истраживања 'Синиша Станковић') (RS-MESTD-inst-2020-200007)
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200116 (Универзитет у Београду, Пољопривредни факултет) (RS-MESTD-inst-2020-200116)
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200043 (Институт за онкологију и радиологију Србије, Београд) (RS-MESTD-inst-2020-200043)
DOI: 10.1002/cbdv.202200069
ISSN: 1612-1872
PubMed: 35213785
WoS: 000768882100001
Scopus: 2-s2.0-85126216260
URI
https://onlinelibrary.wiley.com/doi/10.1002/cbdv.202200069http://www.ncbi.nlm.nih.gov/pubmed/35213785
http://radar.ibiss.bg.ac.rs/handle/123456789/4941